Department of Cardiology, People's Hospital of Qinghai Province, Qinghai, China.
Eur Rev Med Pharmacol Sci. 2017 Oct;21(19):4386-4390.
To explore and discuss the correlation between osteoporosis and the risk factors of cardiovascular diseases in the elderly.
A total of 1240 patients, who were hospitalized in our hospital from January 2012 to January 2017, with the age ≥ 65 years old, were selected. All the patients were divided into osteoporosis group and normal bone mass group according to their bone mineral density. The general conditions, biochemical indexes, combined cardiovascular diseases, and the related risk factors, were recorded and analyzed.
The proportion of patients with coronary heart diseases, hyperlipidemia, diabetes mellitus, and smoking in osteoporosis group was significantly higher than that in normal bone mass group (p < 0.05). Results of binary logistic regression analysis showed that homocysteine (HCY), low density lipoprotein (LDL) and total cholesterol (TC) were the major risk factors of osteoporosis in the elderly patients. High-density lipoprotein (HDL) and body weight were protective factors for senile patients with osteoporosis. Female, hypertension, coronary heart diseases, hyperlipidemia, and diabetes mellitus were the main risk factors of complication in the elderly patients with osteoporosis.
Senile osteoporosis is closely correlated with cardiovascular diseases and related risk factors, including hypertension, coronary heart disease as well as hyperlipidemia, and should be early prevented and treated.
探讨并讨论老年人群中骨质疏松症与心血管疾病相关危险因素的相关性。
选取我院 2012 年 1 月至 2017 年 1 月收治的年龄≥65 岁的 1240 例患者，根据骨密度将所有患者分为骨质疏松组和正常骨量组。记录并分析两组患者的一般情况、生化指标、合并心血管疾病及相关危险因素。
骨质疏松组患者中冠心病、高脂血症、糖尿病、吸烟的比例明显高于正常骨量组（p<0.05）。二元 logistic 回归分析结果显示，同型半胱氨酸（HCY）、低密度脂蛋白（LDL）、总胆固醇（TC）是老年骨质疏松症的主要危险因素，高密度脂蛋白（HDL）、体重是老年骨质疏松症患者的保护因素。女性、高血压、冠心病、高脂血症、糖尿病是老年骨质疏松症患者并发症的主要危险因素。
老年骨质疏松症与心血管疾病及其相关危险因素密切相关，包括高血压、冠心病和高脂血症等，应早期预防和治疗。
