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本文引用的文献

1
Analysis of active surveillance uptake for low-risk localized prostate cancer in Canada: a Canadian multi-institutional study.加拿大低风险局限性前列腺癌主动监测的应用分析:一项加拿大多机构研究。
World J Urol. 2017 Apr;35(4):595-603. doi: 10.1007/s00345-016-1897-0. Epub 2016 Jul 22.
2
Active surveillance for prostate cancer: current evidence and contemporary state of practice.前列腺癌的主动监测:当前证据与当代实践状况
Nat Rev Urol. 2016 Apr;13(4):205-15. doi: 10.1038/nrurol.2016.45. Epub 2016 Mar 8.
3
Active surveillance for prostate cancer: a narrative review of clinical guidelines.主动监测前列腺癌:临床指南的叙述性综述。
Nat Rev Urol. 2016 Mar;13(3):151-67. doi: 10.1038/nrurol.2015.313. Epub 2016 Jan 27.
4
A prospective cohort study of treatment decision-making for prostate cancer following participation in a multidisciplinary clinic.一项关于参与多学科门诊后前列腺癌治疗决策的前瞻性队列研究。
Urol Oncol. 2016 May;34(5):233.e17-25. doi: 10.1016/j.urolonc.2015.11.014. Epub 2015 Dec 15.
5
Molecular Profiles of Prostate Cancer: To Treat or Not to Treat.前列腺癌的分子特征:治疗还是不治疗。
Annu Rev Med. 2016;67:119-35. doi: 10.1146/annurev-med-060413-112226. Epub 2015 Oct 29.
6
Tumor volume in insignificant prostate cancer: Increasing the threshold is a safe approach to reduce over-treatment.微小前列腺癌的肿瘤体积:提高阈值是减少过度治疗的一种安全方法。
Prostate. 2015 Nov;75(15):1768-73. doi: 10.1002/pros.23062. Epub 2015 Aug 18.
7
Patient Decision Making Prior to Radical Prostatectomy: What Is and Is Not Involved.根治性前列腺切除术之前的患者决策:涉及与未涉及的内容。
Am J Mens Health. 2017 Jan;11(1):108-115. doi: 10.1177/1557988315599028. Epub 2016 Sep 21.
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Risk Group and Death From Prostate Cancer: Implications for Active Surveillance in Men With Favorable Intermediate-Risk Prostate Cancer.风险组与前列腺癌死亡:对具有有利中危前列腺癌的男性进行主动监测的影响。
JAMA Oncol. 2015 Jun;1(3):334-40. doi: 10.1001/jamaoncol.2014.284.
9
Systematic Review of Decision Aids for Newly Diagnosed Patients with Prostate Cancer Making Treatment Decisions.对新诊断前列腺癌患者进行治疗决策的决策辅助工具的系统评价。
J Urol. 2015 Nov;194(5):1247-52. doi: 10.1016/j.juro.2015.05.093. Epub 2015 Jun 6.
10
Cognitive factors influencing treatment decision-making in patients with localised prostate cancer: development of a standardised questionnaire.影响局限性前列腺癌患者治疗决策的认知因素:标准化问卷的编制
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加拿大男性对前列腺癌主动监测的看法:对指导和资源的需求。

Canadian Men's perspectives about active surveillance in prostate cancer: need for guidance and resources.

作者信息

Fitch Margaret, Pang Kittie, Ouellet Veronique, Loiselle Carmen, Alibhai Shabbir, Chevalier Simone, Drachenberg Darrel E, Finelli Antonio, Lattouf Jean-Baptiste, Sutcliffe Simon, So Alan, Tanguay Simon, Saad Fred, Mes-Masson Anne-Marie

机构信息

Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, ON, Canada.

Institut du cancer de Montréal and Centre de recherche du Centre hospitalier de l'Université de Montréal, 900 St Denis St, Montreal, QC, Canada.

出版信息

BMC Urol. 2017 Oct 27;17(1):98. doi: 10.1186/s12894-017-0290-7.

DOI:10.1186/s12894-017-0290-7
PMID:29078772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5658971/
Abstract

BACKGROUND

In prostate cancer, men diagnosed with low risk disease may be monitored through an active surveillance. This research explored the perspectives of men with prostate cancer regarding their decision-making process for active surveillance to identify factors that influence their decision and assist health professionals in having conversations about this option.

METHODS

Focus group interviews (n = 7) were held in several Canadian cities with men (N = 52) diagnosed with prostate cancer and eligible for active surveillance. The men's viewpoints were captured regarding their understanding of active surveillance, the factors that influenced their decision, and their experience with the approach. A content and theme analysis was performed on the verbatim transcripts from the sessions.

RESULTS

Patients described their concerns of living with their disease without intervention, but were reassured by the close monitoring under AS while avoiding harmful side effects associated with treatments. Conversations with their doctor and how AS was described were cited as key influences in their decision, in addition to availability of information on treatment options, distrust in the health system, personality, experiences and opinions of others, and personal perspectives on quality of life.

CONCLUSIONS

Men require a thorough explanation on AS as a safe and valid option, as well as guidance towards supportive resources in their decision-making.

摘要

背景

在前列腺癌患者中,被诊断为低风险疾病的男性可能通过主动监测进行观察。本研究探讨了前列腺癌男性患者对于主动监测决策过程的观点,以确定影响其决策的因素,并帮助医疗专业人员就该选择进行沟通。

方法

在加拿大的几个城市对被诊断为前列腺癌且适合主动监测的男性(N = 52)进行了焦点小组访谈(n = 7)。收集了这些男性对于主动监测的理解、影响其决策的因素以及他们对该方法体验的观点。对访谈的逐字记录进行了内容和主题分析。

结果

患者描述了他们对不进行干预而患有疾病的担忧,但在主动监测的密切监测下感到安心,同时避免了与治疗相关的有害副作用。除了治疗选择信息的可获得性、对医疗系统的不信任、个性、他人的经历和意见以及对生活质量的个人看法外,与医生的交谈以及主动监测的描述方式被认为是他们决策的关键影响因素。

结论

男性需要对主动监测作为一种安全有效的选择进行全面解释,以及在其决策过程中提供支持资源的指导。