Geriatric Research Education and Clinical Center, Cleveland Veterans Affairs Medical Center, 10701 East Boulevard, Cleveland, OH 44106, USA; Case Western Reserve University School of Medicine, 10,000 Euclid Avenue, Cleveland, OH 44106, USA.
Infect Dis Clin North Am. 2017 Dec;31(4):743-756. doi: 10.1016/j.idc.2017.07.003.
Recent increases in the incidence of Clostridium difficile infection (CDI) have been observed in all age groups, but the elderly have been disproportionately affected and long-term care facilities (LTCFs) have borne a significant proportion of the increasing burden. Recurrences are common in older adults and may have significant adverse effects on quality of life. Ensuring appropriate diagnostic testing and management is challenging for older adults in the community and in LTCFs. This review focuses on current concepts related to the epidemiology, diagnosis, and management of CDI in older adults.
近年来,各年龄段人群中艰难梭菌感染(CDI)的发病率都有所上升,但老年人受影响的比例不成比例,长期护理机构(LTCFs)承担了很大一部分增加的负担。老年人中复发很常见,可能对生活质量产生重大不利影响。对于社区和长期护理机构中的老年人,确保进行适当的诊断检测和管理具有挑战性。本综述重点介绍了与老年人中 CDI 的流行病学、诊断和管理相关的当前概念。