Division of Infectious Diseases and HIV Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Geriatric Research Education and Clinical Center (GRECC), Louis Stokes Cleveland Department of Veterans Affairs Medical Center (LSCVAMC), Cleveland, OH 44106, USA.
Infect Dis Clin North Am. 2017 Dec;31(4):811-826. doi: 10.1016/j.idc.2017.07.016.
Herpes zoster (HZ) is the result of reactivation of latent varicella zoster virus (VZV) and occurs most frequently in older adults. Classically, HZ presents as a unilateral, selflimited, dermatomal rash. Postherpetic neuralgia (PHN) is a common sequela, presenting as severe pain that persists after the rash has resolved. In the elderly, PHN can be debilitating and requires a prompt diagnosis, treatment with antivirals, and adequate pain control. A longer-term pain management strategy is required if PHN occurs. A modestly effective vaccine exists and is recommended for older individuals.
带状疱疹(HZ)是潜伏水痘带状疱疹病毒(VZV)重新激活的结果,最常发生在老年人中。经典的带状疱疹表现为单侧、自限性、节段性皮疹。带状疱疹后神经痛(PHN)是一种常见的后遗症,表现为皮疹消退后仍持续存在的剧烈疼痛。在老年人中,PHN 可能会使人衰弱,需要及时诊断、抗病毒治疗和充分的疼痛控制。如果发生 PHN,则需要长期的疼痛管理策略。目前存在一种适度有效的疫苗,建议老年人接种。