School of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China.
School of Pharmacy, Yantai University, Yantai 264005, China.
Oxid Med Cell Longev. 2017;2017:9164905. doi: 10.1155/2017/9164905. Epub 2017 Sep 26.
Peony seed oil (PSO) is a novel vegetable oil developed from the seeds of Andr. The present study aimed to make an overall investigation on the chemical profile and antioxidant activities of PSO for reasonable development and utilization of this new resource food. Chemical analysis revealed that PSO was characterized by an uncommon high portion of -linolenic acid (>38%), fairly low ratio of n-6 to n-3 polyunsaturated fatty acids (0.69), and much higher content of -tocopherol than various conventional seed oils. assay indicated that PSO is a more potent scavenger of free radicals than extra virgin olive oil. Moderate intake of PSO exhibited obvious protection against various oxidative damages such as tetrachloromethane-induced acute liver injury in mice and diet-induced hyperlipidemia in rats. The changes in the key indicators of oxidative injury and fatty acid composition in the liver caused by PSO administration were measured, and the results demonstrated that antioxidant properties of PSO are closely related to their characteristic chemical composition. Consequently, the present study provided new evidence for the health implications of PSO, which deserves further development for medical and nutritional use against oxidative damages that are associated with various diseases.
牡丹籽油（PSO）是一种从牡丹籽中开发的新型植物油。本研究旨在全面研究 PSO 的化学特征和抗氧化活性，以合理开发和利用这种新的资源食品。化学分析表明，PSO 的特点是 -亚麻酸含量异常高（>38%），n-6 与 n-3 多不饱和脂肪酸的比例相当低（0.69），比各种常规籽油含有更高的 -生育酚。抗氧化活性测定表明，PSO 是一种比特级初榨橄榄油更有效的自由基清除剂。适量摄入 PSO 对四氯化碳诱导的小鼠急性肝损伤和饮食诱导的大鼠高脂血症等各种氧化损伤具有明显的保护作用。测量了 PSO 给药后肝脏中氧化损伤和脂肪酸组成的关键指标的变化，结果表明 PSO 的抗氧化特性与其特征化学组成密切相关。因此，本研究为 PSO 的健康意义提供了新的证据，值得进一步开发用于医学和营养用途，以对抗与各种疾病相关的氧化损伤。
