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1
Sperm DNA fragmentation testing in male infertility work-up: are we ready?男性不育检查中的精子DNA碎片化检测：我们准备好了吗？
Transl Androl Urol. 2017 Sep;6(Suppl 4):S580-S582. doi: 10.21037/tau.2017.03.81.
2
Should sperm DNA fragmentation testing be included in the male infertility work-up?精子DNA碎片化检测是否应纳入男性不育症检查流程？
Reprod Biomed Online. 2015 Aug;31(2):134-7. doi: 10.1016/j.rbmo.2015.05.006. Epub 2015 May 15.
3
Are we ready to incorporate sperm DNA-fragmentation testing into our male infertility work-up? A plea for more robust studies.我们准备好将精子DNA碎片化检测纳入男性不育症检查流程了吗？呼吁开展更有力的研究。
Reprod Biomed Online. 2015 Feb;30(2):111-2. doi: 10.1016/j.rbmo.2014.12.001. Epub 2014 Dec 11.
4
Is testing of sperm DNA fragmentation (SDF) ready for the basic work-up of male infertility?精子DNA碎片（SDF）检测是否已准备好用于男性不育的基本检查？
Transl Androl Urol. 2017 Sep;6(Suppl 4):S437-S439. doi: 10.21037/tau.2017.03.32.
5
The question of sperm DNA fragmentation testing in the male infertility work-up: a response to Professor Lewis' commentary.男性不育检查中精子DNA碎片化检测的问题：对刘易斯教授评论的回应。
Reprod Biomed Online. 2015 Aug;31(2):138-9. doi: 10.1016/j.rbmo.2015.05.004. Epub 2015 May 15.
6
Analysis on the association between sperm DNA fragmentation index and conventional semen parameters, blood microelements and seminal plasma ROS in male patients with infertility.男性不育患者精子DNA碎片化指数与常规精液参数、血液微量元素及精浆ROS之间的相关性分析
Exp Ther Med. 2018 Jun;15(6):5173-5176. doi: 10.3892/etm.2018.6115. Epub 2018 May 2.
7
A Strengths-Weaknesses-Opportunities-Threats (SWOT) analysis on the clinical utility of sperm DNA fragmentation testing in specific male infertility scenarios.针对特定男性不育症情况中精子DNA碎片检测临床效用的优势-劣势-机会-威胁（SWOT）分析。
Transl Androl Urol. 2017 Sep;6(Suppl 4):S734-S760. doi: 10.21037/tau.2017.08.20.
8
Characterization of Nuclease Activity in Human Seminal Plasma and its Relationship to Semen Parameters, Sperm DNA Fragmentation and Male Infertility.人精浆中核酸酶活性的表征及其与精液参数、精子DNA碎片化和男性不育的关系
J Urol. 2016 Jan;195(1):213-9. doi: 10.1016/j.juro.2015.07.089. Epub 2015 Jul 29.
9
The relationship between sperm viability and DNA fragmentation rates.精子活力与DNA碎片化率之间的关系。
Reprod Biol Endocrinol. 2015 May 14;13:42. doi: 10.1186/s12958-015-0035-y.
10
Associations of sperm DNA fragmentation with lifestyle factors and semen parameters of Saudi men and its impact on ICSI outcome.沙特男性精子 DNA 碎片化与生活方式因素和精液参数的关系及其对 ICSI 结局的影响。
Reprod Biol Endocrinol. 2018 May 19;16(1):49. doi: 10.1186/s12958-018-0369-3.

引用本文的文献

1
Antioxidants for male subfertility.抗氧化剂治疗男性不育。
Cochrane Database Syst Rev. 2022 May 4;5(5):CD007411. doi: 10.1002/14651858.CD007411.pub5.
2
Point-of-care semen analysis of patients with infertility via smartphone and colorimetric paper-based diagnostic device.通过智能手机和比色纸基诊断设备对不育症患者进行即时精液分析。
Bioeng Transl Med. 2020 Aug 18;6(1):e10176. doi: 10.1002/btm2.10176. eCollection 2021 Jan.
3
Antioxidants for male subfertility.用于男性生育力低下的抗氧化剂。
Cochrane Database Syst Rev. 2019 Mar 14;3(3):CD007411. doi: 10.1002/14651858.CD007411.pub4.
4
Implication of sperm processing during assisted reproduction on sperm DNA integrity.辅助生殖过程中精子处理对精子DNA完整性的影响。
Transl Androl Urol. 2017 Sep;6(Suppl 4):S583-S585. doi: 10.21037/tau.2017.04.20.
5
A Strengths-Weaknesses-Opportunities-Threats (SWOT) analysis on the clinical utility of sperm DNA fragmentation testing in specific male infertility scenarios.针对特定男性不育症情况中精子DNA碎片检测临床效用的优势-劣势-机会-威胁（SWOT）分析。
Transl Androl Urol. 2017 Sep;6(Suppl 4):S734-S760. doi: 10.21037/tau.2017.08.20.

本文引用的文献

1
Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios.精子DNA碎片检测的临床应用：基于临床场景的实践建议
Transl Androl Urol. 2016 Dec;5(6):935-950. doi: 10.21037/tau.2016.10.03.
2
Variation of DNA Fragmentation Levels During Density Gradient Sperm Selection for Assisted Reproduction Techniques: A Possible New Male Predictive Parameter of Pregnancy?辅助生殖技术中密度梯度精子筛选过程中DNA片段化水平的变化：一种可能的新的男性妊娠预测参数？
Medicine (Baltimore). 2016 May;95(20):e3624. doi: 10.1097/MD.0000000000003624.
3
Damage to Sperm DNA Mediated by Reactive Oxygen Species: Its Impact on Human Reproduction and the Health Trajectory of Offspring.活性氧介导的精子DNA损伤：其对人类生殖及子代健康轨迹的影响
Adv Exp Med Biol. 2015;868:23-47. doi: 10.1007/978-3-319-18881-2_2.
4
Diagnostic evaluation of the infertile male: a committee opinion.男性不育的诊断评估：委员会意见。
Fertil Steril. 2015 Mar;103(3):e18-25. doi: 10.1016/j.fertnstert.2014.12.103. Epub 2015 Jan 15.
5
The effect of sperm DNA fragmentation on live birth rate after IVF or ICSI: a systematic review and meta-analysis.精子DNA碎片对体外受精或卵胞浆内单精子注射后活产率的影响：一项系统评价和荟萃分析。
Reprod Biomed Online. 2015 Feb;30(2):120-7. doi: 10.1016/j.rbmo.2014.10.018. Epub 2014 Nov 13.
6
Whether sperm deoxyribonucleic acid fragmentation has an effect on pregnancy and miscarriage after in vitro fertilization/intracytoplasmic sperm injection: a systematic review and meta-analysis.精子脱氧核糖核酸碎片化对体外受精/胞浆内单精子注射后妊娠和流产的影响：系统评价和荟萃分析。
Fertil Steril. 2014 Oct;102(4):998-1005.e8. doi: 10.1016/j.fertnstert.2014.06.033. Epub 2014 Sep 1.
7
The clinical utility of sperm DNA integrity testing: a guideline.精子 DNA 完整性检测的临床应用：指南。
Fertil Steril. 2013 Mar 1;99(3):673-7. doi: 10.1016/j.fertnstert.2012.12.049. Epub 2013 Feb 1.
8
The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis.精子 DNA 碎片化对流产率的影响：系统评价和荟萃分析。
Hum Reprod. 2012 Oct;27(10):2908-17. doi: 10.1093/humrep/des261. Epub 2012 Jul 12.
9
Sperm DNA damage measured by the alkaline Comet assay as an independent predictor of male infertility and in vitro fertilization success.精子 DNA 损伤的碱性彗星试验检测作为男性不育和体外受精成功的独立预测因子。
Fertil Steril. 2011 Feb;95(2):652-7. doi: 10.1016/j.fertnstert.2010.08.019. Epub 2010 Sep 22.
10
DNA damage and repair in human oocytes and embryos: a review.人类卵母细胞和胚胎中的DNA损伤与修复：综述
Zygote. 2010 Nov;18(4):357-65. doi: 10.1017/S0967199410000286. Epub 2010 Jul 21.

Sperm DNA fragmentation testing in male infertility work-up: are we ready?

作者信息

Borini Andrea, Tarozzi Nicoletta, Nadalini Marco

机构信息

9.baby, Family and Fertility Center, Bologna, Italy.

出版信息

Transl Androl Urol. 2017 Sep;6(Suppl 4):S580-S582. doi: 10.21037/tau.2017.03.81.

DOI:10.21037/tau.2017.03.81
PMID:29082181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5643714/
Abstract
摘要