Application of sperm DNA fragmentation test in clinical setting.
作者信息
Potdar Neelam
机构信息
Leicester Fertility Centre, University Hospitals of Leicester NHS Trust and University of Leicester, Leicester, UK.
出版信息
Transl Androl Urol. 2017 Sep;6(Suppl 4):S613-S614. doi: 10.21037/tau.2017.05.15.
Abstract
摘要
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Smoking influence on sperm vitality, DNA fragmentation, reactive oxygen species and zinc in oligoasthenoteratozoospermic men with varicocele.吸烟对精索静脉曲张所致少弱畸精子症男性精子活力、DNA碎片、活性氧和锌的影响。
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A Strengths-Weaknesses-Opportunities-Threats (SWOT) analysis on the clinical utility of sperm DNA fragmentation testing in specific male infertility scenarios.针对特定男性不育症情况中精子DNA碎片检测临床效用的优势-劣势-机会-威胁（SWOT）分析。
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本文引用的文献
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An investigation of the potential effect of sperm nuclear vacuoles in human spermatozoa on DNA fragmentation using a neutral and alkaline Comet assay.使用中性和碱性彗星试验研究人类精子中精子核空泡对DNA片段化的潜在影响。
Andrology. 2017 Mar;5(2):392-398. doi: 10.1111/andr.12324.
2
Magnetic cell sorting of semen containing spermatozoa with high DNA fragmentation in ICSI cycles decreases miscarriage rate.在卵胞浆内单精子注射（ICSI）周期中，对含有高DNA碎片率精子的精液进行磁性细胞分选可降低流产率。
Reprod Biomed Online. 2017 May;34(5):506-512. doi: 10.1016/j.rbmo.2017.01.015. Epub 2017 Feb 24.
3
Sperm DNA fragmentation affects epigenetic feature in human male pronucleus.精子DNA片段化影响人类雄原核中的表观遗传特征。
Andrologia. 2018 Feb;50(1). doi: 10.1111/and.12800. Epub 2017 Mar 6.
4
Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios.精子DNA碎片检测的临床应用：基于临床场景的实践建议
Transl Androl Urol. 2016 Dec;5(6):935-950. doi: 10.21037/tau.2016.10.03.
5
Definition and epidemiology of unexplained infertility.不明原因不孕症的定义与流行病学
Obstet Gynecol Surv. 2014 Feb;69(2):109-15. doi: 10.1097/OGX.0000000000000043.
6
Chromosomal abnormalities in embryos derived from testicular sperm extraction.经睾丸精子提取获得的胚胎中的染色体异常。
Fertil Steril. 2003 Jan;79(1):30-8. doi: 10.1016/s0015-0282(02)04407-2.
7
DNA integrity in human spermatozoa: relationships with semen quality.人类精子中的DNA完整性：与精液质量的关系。
J Androl. 2000 Jan-Feb;21(1):33-44.
8
Incidence and main causes of infertility in a resident population (1,850,000) of three French regions (1988-1989).法国三个地区（1988 - 1989年）185万常住人口中的不孕不育发病率及主要原因。
Hum Reprod. 1991 Jul;6(6):811-6. doi: 10.1093/oxfordjournals.humrep.a137433.
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