Beckić S
Acta Med Croatica. 2015 Nov;69(4):253-62.
Functional disorders and diseases are usually diagnosed by exclusion when there is no clear presence of inflammatory, anatomic, metabolic, or neoplastic processes which would explain the symptoms and difficulties of the patient. The Rome III Diagnostic Criteria for Functional Gastrointestinal Disorders (FGID) are used in clinical and scientific medicine. Functional disorders of the upper gastrointestinal system in adults are classified into six groups. Group C are functional bowel disorders which include irritable bowel syndrome (C1), functional bloating (C2), functional constipation (C3) and functional diarrhea (4). The symptoms of functional gastrointestinal disorders are often a combination of disrupted physiological functions, such as an increase in motor reactivity of the intestine, visceral hypersensitivity, impaired immune functions and inflammatory intestinal mucosa followed by change in the intestinal bacterial flora and disrupted central nervous system-enteric nervous system regulation because of exposure to different psychosocial and sociocultural factors. The symptoms must be present for at least six months before clinical manifestation of the disease and also must be currently present and diagnostically confirmed in the last three months. Diagnostic procedures are targeted individually, depending on the patient age, nature of symptoms, and other clinical and laboratory characteristics. Treatment is based on health education, nutrition counseling, medication and psychological support.
当不存在可解释患者症状和问题的明确炎症、解剖、代谢或肿瘤过程时,功能性障碍和疾病通常通过排除法进行诊断。功能性胃肠疾病(FGID)的罗马III诊断标准用于临床和科学医学。成 人上消化道系统的功能性障碍分为六组。C组是功能性肠病,包括肠易激综合征(C1)、功能性腹胀(C2)、功能性便秘(C3)和功能性腹泻(C4)。功能性胃肠疾病的症状通常是生理功能紊乱的组合,如肠道运动反应性增加、内脏超敏反应、免疫功能受损和肠黏膜炎症,随后是肠道菌群变化以及由于暴露于不同的心理社会和社会文化因素而导致的中枢神经系统 - 肠神经系统调节紊乱。症状必须在疾病临床表现前至少出现六个月,并且在过去三个月内必须持续存在并经诊断确认。诊断程序根据患者年龄、症状性质以及其他临床和实验室特征进行个体化。治疗基于健康教育、营养咨询、药物治疗和心理支持。