Thompson W G, Heaton K W
Gastroenterology. 1980 Aug;79(2):283-8.
Symptoms of functional gastrointestinal disorder were sought by a questionnaire administered to 301 apparently healthy subjects in young, middle-aged, and elderly categories. Abdominal pain, a feeling of incomplete evaculation after defecation, urgency, scybala, runny stools, straining at stool, borborygmi, distension, heartburn, and laxative use were all very common. The typical symptom pattern of the spastic irritable bowel syndrome (IBS) occurred in 13.6% of subjects. Seven percent suffered noncolonic pain that was commonly associated with heartburn. A further 3.7% had painless diarrhea without the features of the spastic IBS. Six percent suffered painless constipation. Constipation seemed to increase with age. Thus four clinically distinct functional bowel syndromes existed in almost one-third of the subjects studied. Most of these had not consulted a doctor. Hospital-based studies of the IBS derive from a selected minority of patients and may not be applicable to all sufferers.
通过对301名年龄涵盖青年、中年和老年的表面健康受试者进行问卷调查，来探寻功能性胃肠疾病的症状。腹痛、排便后仍有未排空感、便急、粪块、稀便、排便费力、肠鸣音、腹胀、烧心以及使用泻药等情况都非常常见。痉挛性肠易激综合征（IBS）的典型症状模式出现在13.6%的受试者中。7%的受试者有非结肠性疼痛，且通常伴有烧心症状。另外3.7%的受试者有无痛性腹泻，但不具备痉挛性IBS的特征。6%的受试者有无痛性便秘。便秘似乎随着年龄增长而增多。因此，在所研究的近三分之一受试者中存在四种临床上不同的功能性肠综合征。其中大多数人未曾咨询过医生。基于医院的IBS研究来自少数经过挑选的患者，可能并不适用于所有患者。
