无机包覆纳米晶体向水相介质的转移。

Transfer of Inorganic-Capped Nanocrystals into Aqueous Media.

作者信息

Guhrenz Chris, Sayevich Vladimir, Weigert Florian, Hollinger Eileen, Reichhelm Annett, Resch-Genger Ute, Gaponik Nikolai, Eychmüller Alexander

机构信息

Physical Chemistry, Technische Universität Dresden , Bergstr. 66b, 01062 Dresden, Germany.

BAM Federal Institute for Materials Research and Testing , Division Biophotonics, Richard-Willstätter Str. 11, 12489 Berlin, Germany.

出版信息

J Phys Chem Lett. 2017 Nov 16;8(22):5573-5578. doi: 10.1021/acs.jpclett.7b02319. Epub 2017 Nov 2.

DOI:10.1021/acs.jpclett.7b02319

PMID:29083902

Abstract

We report on a novel and simple approach to surface ligand design of CdSe-based nanocrystals (NCs) with biocompatible, heterobifunctional polyethylene glycol (PEG) molecules. This method provides high transfer yields of the NCs into aqueous media with preservation of the narrow and symmetric emission bands of the initial organic-capped NCs regardless of their interior crystal structure and surface chemistry. The PEG-functionalized NCs show small sizes, high photoluminescence quantum yields of up to 75%, as well as impressive optical and colloidal stability. This universal approach is applied to different fluorescent nanomaterials (CdSe/CdS, CdSe/CdSCdZnS, and CdSe/CdS/ZnS), extending the great potential of organic-capped NCs for biological applications.

摘要

我们报道了一种新颖且简单的方法，用于基于CdSe的纳米晶体（NCs）与具有生物相容性的异双功能聚乙二醇（PEG）分子进行表面配体设计。该方法能将NCs高效转移至水相介质中，且不论其内部晶体结构和表面化学性质如何，均可保留初始有机封端NCs窄而对称的发射带。PEG功能化的NCs尺寸小，光致发光量子产率高达75%，并具有出色的光学和胶体稳定性。这种通用方法适用于不同的荧光纳米材料（CdSe/CdS、CdSe/CdSCdZnS和CdSe/CdS/ZnS），拓展了有机封端NCs在生物应用方面的巨大潜力。