Iwamoto Genta, Kawahara Takashi, Tanabe Mikiko, Ninomiya Sahoko, Takamoto Daiji, Mochizuki Taku, Kuroda Shinnosuke, Takeshima Teppei, Izumi Koji, Hattori Yusuke, Teranishi Jun-Ichi, Yumura Yasushi, Miyoshi Yasuhide, Uemura Hiroji
Division of Diagnostic Pathology, Yokohama City University Medical Center, Yokohama, Japan.
Departments of Urology and Renal Transplantation, Yokohama City University Medical Center, Yokohama, Japan.
J Med Case Rep. 2017 Oct 31;11(1):306. doi: 10.1186/s13256-017-1473-2.
Paraganglioma is an extra site of pheochromocytoma. Paraganglioma in the bladder is a very rare disease accounting for 0.06% of all bladder tumors.
A 77-year-old Japanese man was referred to our department for the further examination of a bladder tumor detected on preoperative computed tomography of his gastric cancer. Cystoscopy revealed a submucosal tumor in the upper area of his bladder, so transurethral resection of the bladder tumor was performed. During transurethral resection of the bladder tumor, his blood pressure sharply increased, and a pathological examination showed paraganglioma in his bladder. Postoperative I-123-metaiodobenzylguanidine scintigraphy detected a higher intake of his bladder tumor. Laboratory examinations showed a slightly increased noradrenaline level of 530 pg/ml and reduced platelet count at 167,000/μL. Based on the progression of his gastric cancer, no additional therapy was performed on his bladder tumor. Eight months after surgery, he died from aspiration pneumonitis.
Here we report a rare case of paraganglioma in the bladder. We discuss paraganglioma based on previous studies.
副神经节瘤是嗜铬细胞瘤的一个额外发病部位。膀胱副神经节瘤是一种非常罕见的疾病，占所有膀胱肿瘤的0.06%。
一名77岁的日本男性因在术前对其胃癌进行计算机断层扫描时发现膀胱肿瘤而被转诊至我科。膀胱镜检查发现其膀胱上部区域有一个黏膜下肿瘤，因此进行了经尿道膀胱肿瘤切除术。在经尿道膀胱肿瘤切除术中，他的血压急剧升高，病理检查显示其膀胱中有副神经节瘤。术后I-123-间碘苄胍闪烁显像检测到其膀胱肿瘤摄取增加。实验室检查显示去甲肾上腺素水平略有升高，为530 pg/ml，血小板计数降低，为167,000/μL。基于其胃癌的进展情况，未对其膀胱肿瘤进行额外治疗。术后八个月，他死于吸入性肺炎。
在此，我们报告一例罕见的膀胱副神经节瘤病例。我们根据先前的研究对副神经节瘤进行了讨论。
