Mehmood Yassir, Gupta Rahul, Mahajan Arti, Rahman Yaser, Gupta Kshitij
Department of Urology and Renal Transplant, Government Medical College, Jammu 180001, Jammu and Kashmir, India.
Department of Anesthesia and Critical Care, Government Medical College, Jammu 180001, Jammu and Kashmir, India.
Bladder (San Franc). 2025 Jun 24;12(3):e21200052. doi: 10.14440/bladder.2024.0064. eCollection 2025.
Pheochromocytomas originate from chromaffin cells of the adrenal medulla, resulting in excessive production of catecholamines and bizarre clinical symptoms. An extra-adrenal pheochromocytoma is called a paraganglioma. Urinary bladder paraganglioma represents an uncommon tumor that accounts for <0.05% of all bladder tumors.
Presented here are three cases of incidental urinary bladder paraganglioma, all having hematuria as the primary symptom. During transurethral resection of bladder tumor, blood pressure fluctuated intensely with profuse bleeding, leading to the abandonment of the procedure. The patients were later diagnosed as having paraganglioma, and then, they were subjected to systemic evaluation and definitive treatment.
Although bladder paraganglioma is a rare condition, it should be strongly suspected if a patient who has no definitive symptoms of the disease developed a sudden hemodynamic change at the very start of the procedure.
嗜铬细胞瘤起源于肾上腺髓质的嗜铬细胞，导致儿茶酚胺过度分泌并出现奇异的临床症状。肾上腺外嗜铬细胞瘤称为副神经节瘤。膀胱副神经节瘤是一种罕见肿瘤，占所有膀胱肿瘤的比例小于0.05%。
本文介绍三例偶然发现的膀胱副神经节瘤病例，均以血尿为主要症状。在经尿道膀胱肿瘤切除术中，血压剧烈波动且出血量大，导致手术中断。患者随后被诊断为副神经节瘤，接着接受了全面评估和确定性治疗。
尽管膀胱副神经节瘤罕见，但如果在手术开始时没有明确疾病症状的患者突然出现血流动力学改变，应高度怀疑此病。
