I类DNA Pvu II限制性HLA基因片段与血清学等位基因的相关性。
Correlation of class I DNA Pvu II restriction HLA gene fragments with serologic alleles.
作者信息
Lucotte G, Coulondre C, Salmon C
机构信息
Laboratoire de Génétique Moléculaire du CNTS-Institut, Paris, France.
出版信息
Exp Clin Immunogenet. 1985;2(4):191-7.
PMID:2908502
Abstract
Restriction enzyme site polymorphisms for Pvu II endonuclease are examined in a panel of DNAs isolated from peripheral blood lymphocytes of HLA-typed individuals. 21 polymorphic bands are detected from a total of 39 restriction fragments analyzed, only 9 of them corresponding to common variable morphs. Three polymorph fragments only correlate with known HLA-A and -B serologic alleles.
摘要
在一组从HLA分型个体的外周血淋巴细胞中分离出的DNA中，检测了Pvu II核酸内切酶的限制性酶切位点多态性。在总共分析的39个限制性片段中检测到21条多态性条带，其中只有9条对应于常见的可变形态。三个多态性片段仅与已知的HLA - A和 - B血清学等位基因相关。
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