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失代偿期肝硬化患者的医院再入院:指向预防策略的因素。

Hospital readmissions in decompensated cirrhotics: Factors pointing toward a prevention strategy.

机构信息

Massachusetts General Hospital, Division of Gastroenterology, Boston, MA 02114, United States.

Duke University Hospital, Department of Medicine, Durham, NC 27710, United States.

出版信息

World J Gastroenterol. 2017 Oct 7;23(37):6868-6876. doi: 10.3748/wjg.v23.i37.6868.

Abstract

AIM

To reduce readmissions and improve patient outcomes in cirrhotic patients through better understanding of readmission predictors.

METHODS

We performed a single-center retrospective study of patients admitted with decompensated cirrhosis from January 1, 2011 to December 31, 2013 ( = 222). Primary outcomes were time to first readmission and 30-d readmission rate due to complications of cirrhosis. Clinical and demographic data were collected to help describe predictors of readmission, along with care coordination measures such as post-discharge status and outpatient follow-up. Univariate and multivariate analyses were performed to describe variables associated with readmission.

RESULTS

One hundred thirty-two patients (59.4%) were readmitted at least once during the study period. Median time to first and second readmissions were 54 and 93 d, respectively. Thirty and 90-d readmission rates were 20.7 and 30.1 percent, respectively. Predictors of 30-d readmission included education level, hepatic encephalopathy at index, ALT more than upper normal limit and Medicare coverage. There were no statistically significant differences in readmission rates when stratified by discharge disposition, outpatient follow-up provider or time to first outpatient visit.

CONCLUSION

Readmissions are challenging aspect of care for cirrhotic patients and risk continues beyond 30 d. More initiatives are needed to develop enhanced, longitudinal post-discharge systems.

摘要

目的

通过更好地了解再入院预测因素,减少肝硬化患者的再入院率并改善患者的预后。

方法

我们对 2011 年 1 月 1 日至 2013 年 12 月 31 日(= 222)因失代偿性肝硬化入院的患者进行了一项单中心回顾性研究。主要结局是首次再入院时间和因肝硬化并发症导致的 30 天再入院率。收集临床和人口统计学数据以帮助描述再入院的预测因素,以及出院后的状态和门诊随访等护理协调措施。进行了单因素和多因素分析,以描述与再入院相关的变量。

结果

在研究期间,132 名患者(59.4%)至少再入院一次。首次和第二次再入院的中位时间分别为 54 和 93 天。30 天和 90 天的再入院率分别为 20.7%和 30.1%。30 天再入院的预测因素包括教育程度、指数时肝性脑病、ALT 高于正常值上限和医疗保险覆盖范围。根据出院安置、门诊随访提供者或首次门诊就诊时间分层,再入院率没有统计学差异。

结论

再入院是肝硬化患者护理的一个挑战方面,风险持续时间超过 30 天。需要更多的举措来开发强化的、纵向的出院后系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d471/5645619/58b4cd27234c/WJG-23-6868-g001.jpg

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