Berhe Simon, Danzer Enrico, Meyers Paul, Behr Gerald, LaQuaglia Michael P, Price Anita P
Pediatric Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
J Pediatr Surg Case Rep. 2018 Jan;28:13-16. doi: 10.1016/j.epsc.2017.09.022.
Intraabdominal metastases in the setting of osteosarcoma are very rare. We describe a case of a 17-year-old boy with high-grade right distal femur osteosarcoma who two years after diagnosis developed extensive intra abdominal metastases involving the omentum, peritoneum, bowel serosa, psoas muscles and abdominal soft tissue. Awareness of and surveillance for unusual patterns of metastasis may allow for earlier detection, intervention, and palliative care decision-making, which may affect survival and quality of life. This report underlines the need for prospective studies evaluating surveillance guidelines for patients after medical and surgical management of osteosarcoma, especially in cases complicated by pulmonary metastases.
骨肉瘤患者发生腹腔内转移非常罕见。我们报告一例17岁男性,患有高级别右股骨远端骨肉瘤,诊断两年后出现广泛的腹腔内转移,累及大网膜、腹膜、肠浆膜、腰大肌和腹部软组织。认识并监测转移的异常模式可能有助于早期发现、干预及做出姑息治疗决策,这可能会影响患者的生存和生活质量。本报告强调有必要开展前瞻性研究,评估骨肉瘤患者接受药物及手术治疗后的监测指南,尤其是在合并肺转移的病例中。