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前腭成形术治疗阻塞性睡眠呼吸暂停——一项系统评价

Anterior palatoplasty in the treatment of obstructive sleep apnoea - a systemic review.

作者信息

Pang K P, Pang E B, Pang K A, Rotenberg B

机构信息

Consultant, Otolaryngology, Asia Sleep Centre, Paragon, Singapore.

Student, Otolaryngology, Asia Sleep Centre, Paragon, Singapore.

出版信息

Acta Otorhinolaryngol Ital. 2018 Feb;38(1):1-6. doi: 10.14639/0392-100X-1641. Epub 2017 Oct 31.

Abstract

This study seeks to determine the objective and subjective success rates of anterior palatoplasty and its variants for the treatment of obstructive sleep apnoea (OSA). A systematic review with two independent searches of Medline, PubMed, Cochrane Library and Evidence Based Medicine Reviews was performed to identify publications relevant to OSA and anterior palatoplasty. All relevant studies published before 30 June 2015 were included. Six studies were included in the systematic review. The numbers of patients in each paper ranged from 13 to 77 (total = 240), and mean age ranged from 21 to 51 years. Substantial and consistent improvement in polysomnography (PSG) outcomes were observed in patients after the anterior palatoplasty, with or without multilevel surgery. The results showed that the anterior palatoplasty technique provides significantly improvement in the post-operative Apnoea-Hypopnea Index. The mean pre-operative AHI (in the 6 papers) improved from 16.3 to 7.1, the snore visual analogue scale improved from 7.5 to 3.1 and the Epworth score reduced from 11.3 to 7.3 post-operatively. The overall pro-rated pooled success rate for all the patients was 72.5%, with a mean follow-up of 17.3 months. Anterior palatoplasty is an effective option in the management of patients with mild to moderate OSA.

摘要

本研究旨在确定前腭成形术及其变体治疗阻塞性睡眠呼吸暂停(OSA)的客观和主观成功率。通过对Medline、PubMed、Cochrane图书馆和循证医学评论进行两次独立检索的系统评价,以识别与OSA和前腭成形术相关的出版物。纳入了2015年6月30日前发表的所有相关研究。系统评价纳入了6项研究。每篇论文中的患者数量从13例到77例不等(总计240例),平均年龄从21岁到51岁。在前腭成形术患者中,无论是否进行多级手术,多导睡眠图(PSG)结果均有显著且持续的改善。结果表明,前腭成形术技术在术后呼吸暂停低通气指数方面有显著改善。(6篇论文中的)术前平均AHI从16.3改善至7.1,鼾声视觉模拟量表从7.5改善至3.1,Epworth评分术后从11.3降至7.3。所有患者的总体按比例合并成功率为72.5%,平均随访17.3个月。前腭成形术是治疗轻至中度OSA患者的有效选择。

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