Shah Zahid Hussain, Rehman Hafiz M, Akhtar Tasneem, Daur Ihsanullah, Nawaz Muhammad A, Ahmad Muhammad Q, Rana Iqrar A, Atif Rana M, Yang Seung H, Chung Gyuhwa
Department of Arid Land Agriculture, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Electronics and Biomedical Engineering, Chonnam National University, Yeosu, South Korea.
Front Genet. 2017 Oct 17;8:141. doi: 10.3389/fgene.2017.00141. eCollection 2017.
Systems biology and omics has provided a comprehensive understanding about the dynamics of the genome, metabolome, transcriptome, and proteome under stress. In wheat, abiotic stresses trigger specific networks of pathways involved in redox and ionic homeostasis as well as osmotic balance. These networks are considerably more complicated than those in model plants, and therefore, counter models are proposed by unifying the approaches of omics and stress systems biology. Furthermore, crosstalk among these pathways is monitored by the regulation and streaming of transcripts and genes. In this review, we discuss systems biology and omics as a promising tool to study responses to oxidative, salinity, and drought stress in wheat.
系统生物学和组学已使人们对胁迫下基因组、代谢组、转录组和蛋白质组的动态变化有了全面的认识。在小麦中,非生物胁迫会触发参与氧化还原和离子稳态以及渗透平衡的特定途径网络。这些网络比模式植物中的网络复杂得多,因此,通过整合组学和胁迫系统生物学的方法提出了相应的模型。此外,这些途径之间的相互作用通过转录本和基因的调控与流动来监测。在本综述中,我们讨论了系统生物学和组学作为研究小麦对氧化、盐度和干旱胁迫响应的一种有前景的工具。