1 Department of Radiology, Scott & White Medical Center, Texas A&M University Health Sciences, 2401 S 31st St, MS-01-W256, Temple, TX 76508.
2 Department of Radiology and Comprehensive Cancer Center, Michigan Medicine, University of Michigan, Ann Arbor, MI.
AJR Am J Roentgenol. 2018 Feb;210(2):285-291. doi: 10.2214/AJR.17.18629. Epub 2017 Nov 1.
The discovery of breast cancer at earlier stages with screening brings the risk that some cancers will be overdiagnosed or overtreated. Reasonable estimates show the overdiagnosis rate due to screening mammography to be low, 1-10%.
Overdiagnosis should not be used as a reason to delay the onset or decrease the frequency of screening, because neither strategy will decrease overdiagnosis. Improvements in personalized treatment will diminish the morbidity of treatment and, therefore, the significance of overdiagnosis.
通过筛查更早地发现乳腺癌会带来某些癌症被过度诊断或过度治疗的风险。合理的估计显示，由于筛查性乳房 X 光摄影，过度诊断的发生率较低，为 1-10%。
不应该将过度诊断作为延迟筛查开始或降低筛查频率的理由，因为这两种策略都不会减少过度诊断。个性化治疗的改进将降低治疗的发病率，从而降低过度诊断的意义。
