人类细胞图谱：技术方法与挑战。
The Human Cell Atlas: Technical approaches and challenges.
机构信息
RIKEN Center for Life Science Technologies, Division of Genomic Technologies, Yokohama, Kanagawa, Japan.
Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
出版信息
Brief Funct Genomics. 2018 Jul 1;17(4):283-294. doi: 10.1093/bfgp/elx029.
The Human Cell Atlas is a large, international consortium that aims to identify and describe every cell type in the human body. The comprehensive cellular maps that arise from this ambitious effort have the potential to transform many aspects of fundamental biology and clinical practice. Here, we discuss the technical approaches that could be used today to generate such a resource and also the technical challenges that will be encountered.
人类细胞图谱是一个大型的国际合作组织，旨在鉴定和描述人体中的每一种细胞类型。这项雄心勃勃的工作所产生的全面细胞图谱有可能彻底改变基础生物学和临床实践的许多方面。在这里，我们讨论了今天可以用来生成此类资源的技术方法，以及将要遇到的技术挑战。
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