Presence of pancreatic-type phospholipase A2 mRNA in rat gastric mucosa and lung.

作者信息

Sakata T, Nakamura E, Tsuruta Y, Tamaki M, Teraoka H, Tojo H, Ono T, Okamoto M

机构信息

Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.

出版信息

Biochim Biophys Acta. 1989 Jan 23;1007(1):124-6. doi: 10.1016/0167-4781(89)90141-3.

The content of mRNA for a pancreatic-type phospholipase A2 present in rat gastric mucosa was much greater than that in pancreas. In lung the mRNA for this pancreatic-type phospholipase A2 was also detected, but less than in pancreas. Nucleotide sequence analysis showed that these pancreatic-type phospholipase A2 cDNAs derived from rat gastric mucosa and lung were completely identical to that from rat pancreas (Ohara et al. (1986) J. Biochem. 99, 733-739). This demonstrates that the pancreatic-type phospholipase A2 present in gastric mucosa and lung does not originate from pancreas.