Norton Isaiah, Essayed Walid Ibn, Zhang Fan, Pujol Sonia, Yarmarkovich Alex, Golby Alexandra J, Kindlmann Gordon, Wassermann Demian, Estepar Raul San Jose, Rathi Yogesh, Pieper Steve, Kikinis Ron, Johnson Hans J, Westin Carl-Fredrik, O'Donnell Lauren J
Brigham & Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Isomics, Inc., Cambridge, Massachusetts.
Cancer Res. 2017 Nov 1;77(21):e101-e103. doi: 10.1158/0008-5472.CAN-17-0332.
Diffusion MRI (dMRI) is the only noninvasive method for mapping white matter connections in the brain. We describe SlicerDMRI, a software suite that enables visualization and analysis of dMRI for neuroscientific studies and patient-specific anatomic assessment. SlicerDMRI has been successfully applied in multiple studies of the human brain in health and disease, and here, we especially focus on its cancer research applications. As an extension module of the 3D Slicer medical image computing platform, the SlicerDMRI suite enables dMRI analysis in a clinically relevant multimodal imaging workflow. Core SlicerDMRI functionality includes diffusion tensor estimation, white matter tractography with single and multi-fiber models, and dMRI quantification. SlicerDMRI supports clinical DICOM and research file formats, is open-source and cross-platform, and can be installed as an extension to 3D Slicer (www.slicer.org). More information, videos, tutorials, and sample data are available at dmri.slicer.org .
扩散磁共振成像（dMRI）是绘制大脑白质连接的唯一非侵入性方法。我们介绍了SlicerDMRI，这是一个软件套件，可用于神经科学研究和针对患者的解剖学评估的dMRI可视化与分析。SlicerDMRI已成功应用于多项关于健康和患病人类大脑的研究，在此，我们特别关注其在癌症研究中的应用。作为3D Slicer医学图像计算平台的扩展模块，SlicerDMRI套件可在临床相关的多模态成像工作流程中进行dMRI分析。SlicerDMRI的核心功能包括扩散张量估计、使用单纤维和多纤维模型的白质纤维束成像以及dMRI定量分析。SlicerDMRI支持临床DICOM和研究文件格式，是开源且跨平台的，可作为3D Slicer（www.slicer.org）的扩展进行安装。更多信息、视频、教程和示例数据可在dmri.slicer.org获取。
