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猫咬伤后新发现的犬二氧化碳嗜纤维菌引起的脓毒症:犬二氧化碳嗜纤维菌是继犬咬二氧化碳嗜纤维菌和犬龈二氧化碳嗜纤维菌之后引起人畜共患病感染的第三种病原体。

Sepsis Caused by Newly Identified Capnocytophaga canis Following Cat Bites: C. canis Is the Third Candidate along with C. canimorsus and C. cynodegmi Causing Zoonotic Infection.

作者信息

Taki Minami, Shimojima Yoshio, Nogami Ayako, Yoshida Takuhiro, Suzuki Michio, Imaoka Koichi, Momoi Hiroki, Hanyu Norinao

机构信息

Department of Neurology, Iida Municipal Hospital, Japan.

Department of Clinical Laboratory, Iida Municipal Hospital, Japan.

出版信息

Intern Med. 2018 Jan 15;57(2):273-277. doi: 10.2169/internalmedicine.9196-17. Epub 2017 Nov 1.

DOI:10.2169/internalmedicine.9196-17
PMID:29093403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5820050/
Abstract

Sepsis caused by a Capnocytophaga canis infection has only been rarely reported. A 67-year-old female with a past medical history of splenectomy was admitted to our hospital with fever and general malaise. She had been bitten by a cat. She showed disseminated intravascular coagulation and multi-organ failure because of severe sepsis. On blood culture, characteristic gram-negative fusiform rods were detected; therefore, a Capnocytophaga species infection was suspected. A nucleotide sequence analysis revealed the species to be C. canis, which was newly identified in 2016. C. canis may have low virulence in humans; however, C. canis with oxidase activity may cause severe zoonotic infection.

摘要

犬二氧化碳嗜纤维菌感染引起的败血症鲜有报道。一名有脾切除病史的67岁女性因发热和全身不适入住我院。她曾被猫咬伤。由于严重败血症,她出现了弥散性血管内凝血和多器官功能衰竭。血培养检测到特征性革兰氏阴性梭形杆菌;因此,怀疑是二氧化碳嗜纤维菌属感染。核苷酸序列分析显示该菌种为犬二氧化碳嗜纤维菌,于2016年新发现。犬二氧化碳嗜纤维菌在人类中可能毒力较低;然而,具有氧化酶活性的犬二氧化碳嗜纤维菌可能会引起严重的人畜共患感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf7/5820050/6eebbb5600bd/1349-7235-57-0273-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf7/5820050/9530b39f8a48/1349-7235-57-0273-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf7/5820050/994bdd3c0536/1349-7235-57-0273-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf7/5820050/6eebbb5600bd/1349-7235-57-0273-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf7/5820050/9530b39f8a48/1349-7235-57-0273-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf7/5820050/994bdd3c0536/1349-7235-57-0273-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aaf7/5820050/6eebbb5600bd/1349-7235-57-0273-g003.jpg

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本文引用的文献

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Only a subset of C. canimorsus strains is dangerous for humans.只有一部分犬咬二氧化碳嗜纤维菌菌株对人类有危险。
Emerg Microbes Infect. 2016 Mar 23;5(3):e29. doi: 10.1038/emi.2016.43.
2
Whole genome sequencing identifies a novel species of the genus Capnocytophaga isolated from dog and cat bite wounds in humans.全基因组测序鉴定出一种从人类狗咬伤和猫咬伤伤口中分离出的嗜二氧化碳噬纤维菌属新物种。
Sci Rep. 2016 Mar 7;6:22919. doi: 10.1038/srep22919.
3
Capnocytophaga canimorsus: an emerging cause of sepsis, meningitis, and post-splenectomy infection after dog bites.
经迁移的猫传播的潜在相关的虫媒病原体和其他病原体。
Parasit Vectors. 2022 Nov 8;15(1):415. doi: 10.1186/s13071-022-05553-8.
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Cellulitis and transient bacteremia by after a cat scratch in an immunocompetent patient.免疫功能正常的患者被猫抓伤后发生蜂窝织炎和短暂菌血症。
Access Microbiol. 2022 May 18;4(5):acmi000352. doi: 10.1099/acmi.0.000352. eCollection 2022 Aug.
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