Rahmani Koorosh, Taghipour Zahir Shokouh, Baghi Yazdi Mohammad, Navabazam Alireza
Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Case Rep Med. 2017;2017:2324717. doi: 10.1155/2017/2324717. Epub 2017 Sep 28.
Adenoid cystic carcinoma (ACC) is a rare malignant tumor, mostly involving the minor salivary glands. Herein, we present a case of ACC in a 43-year-old man with symptoms of dental abscess as the initial presentation of the tumor. In spiral computed tomography (CT) scan, soft tissue mass with the erosion of maxillary sinus wall on the right side of the alveolar ridge was evident. Histopathological examination of the excised tumor with immunohistochemical studies (C-kit, Vimentin, pan-cytokeratin, p53, p63, and ki67 positive reaction) confirmed grade 2 ACC in the maxillary sinus. The patient underwent hemimaxillectomy and right-neck dissection. Due to the extension of tumor cells excessively into the surrounding tissues and involvement of orbital bone, complete and total resection of the tumor with safe margins could not be done. After surgery, adjuvant radiotherapy was considered for the patient. At the end of treatment, the patient lost his eye vision. Seventeen months from initial diagnosis, he was still alive without lung or distant metastasis.
腺样囊性癌（ACC）是一种罕见的恶性肿瘤，主要累及小唾液腺。在此，我们报告一例43岁男性的腺样囊性癌病例，该患者最初表现为牙脓肿症状。在螺旋计算机断层扫描（CT）中，可见牙槽嵴右侧有软组织肿块并伴有上颌窦壁侵蚀。对切除肿瘤进行组织病理学检查并结合免疫组织化学研究（C-kit、波形蛋白、全细胞角蛋白、p53、p63和ki67呈阳性反应），证实上颌窦为2级腺样囊性癌。患者接受了半侧上颌骨切除术和右侧颈部清扫术。由于肿瘤细胞过度延伸至周围组织且累及眶骨，无法实现肿瘤的完全切除及安全切缘。术后，考虑对患者进行辅助放疗。治疗结束时，患者失去了视力。自初次诊断起17个月，他仍存活，无肺转移或远处转移。
