Muto Haruka, Ishii Keisuke, Nakano Takahiro, Hayashi Shusaku, Okamoto Yoko, Mitsuda Nobuaki
Department of Obstetrics, Osaka Women's and Children's Hospital, Izumi, Japan.
J Obstet Gynaecol Res. 2018 Feb;44(2):217-222. doi: 10.1111/jog.13522. Epub 2017 Nov 2.
The aim of this study was to determine the effect of maternal age on emergency cesarean section (CS) during labor, and to identify the independent risk factors for emergency CS.
This was a retrospective cohort study using data from 2009 to 2014 from a tertiary perinatal care center in Japan. Inclusion criteria were maternal age ≥ 35 years, nulliparous singleton pregnancy at term and a cephalic presentation without indication of elective CS at onset of labor. The primary outcome was rate of emergency CS, while independent risk factors were elucidated using multivariate logistic regression analysis.
Of 953 women, 199 (20.9%) delivered by emergency CS. Rates of emergency CS were 18.3% (129/706) in women aged 35-39 years and 28.3% (70/247) in those aged ≥ 40 years (P < 0.01). Adjusted odds ratios (95% confidence intervals) of independent risk factors were 1.50 (1.03-2.18) for maternal age ≥ 40 years, 1.51 (1.06-2.17) for body mass index ≥ 25 kg/m , 2.22 (1.24-3.98) for hypertensive disorder during pregnancy, 3.43 (1.31-8.95) for large-for-date fetus and 4.64 (3.23-6.69) for induction of labor.
The rate of intrapartum emergency CS in older nulliparous women at term was approximately 21%. Induction of labor should be recognized as a significant factor for emergency CS.
本研究旨在确定产妇年龄对分娩期间急诊剖宫产的影响,并确定急诊剖宫产的独立危险因素。
这是一项回顾性队列研究,使用了日本一家三级围产期护理中心2009年至2014年的数据。纳入标准为产妇年龄≥35岁、足月单胎初产妇、头先露且分娩开始时无选择性剖宫产指征。主要结局是急诊剖宫产率,同时使用多因素逻辑回归分析阐明独立危险因素。
953名女性中,199名(20.9%)通过急诊剖宫产分娩。35至39岁女性的急诊剖宫产率为18.3%(129/706),40岁及以上女性为28.3%(70/247)(P<0.01)。独立危险因素的调整优势比(95%置信区间)为:产妇年龄≥40岁时为1.50(1.03 - 2.18),体重指数≥25kg/m²时为1.51(1.06 - 2.17),孕期高血压疾病时为2.22(1.24 - 3.98),巨大胎儿时为3.43(1.31 - 8.95),引产时为4.64(3.23 - 6.69)。
足月初产高龄女性产时急诊剖宫产率约为21%。引产应被视为急诊剖宫产的一个重要因素。