Guan Ping, Tang Fei, Sun Guoqiang, Ren Wei
Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, Wuhan, China.
Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, Wuhan, China
J Investig Med. 2020 Mar;68(3):799-806. doi: 10.1136/jim-2019-001175. Epub 2020 Jan 24.
To analyze the maternal and fetal factors affecting emergency cesarean section (EmCS) and establish a risk scoring system to quantitatively predict the risk of EmCS.
A total of 10,295 pregnant women were enrolled in this study. The influence of maternal and fetal factors on the risk of EmCS was analyzed.
991 (9.63%) cases of failed vaginal delivery received EmCS. The two main causes of EmCS were fetal distress (67.21%) and abnormal fetal position (14.93%). There were significant differences in 17 maternal and fetal factors between the normal vaginal delivery (NVD) and EmCS groups (p<0.05 for all). Univariate and multivariate regression analyses showed that nine maternal and infant factors were independent risk factors (p<0.05 for all). The major factors were abnormal quantity of amniotic fluid (OR 6.867, 95% CI 4.442 to 10.618), nulliparous (OR 4.336, 95% CI 3.074 to 6.115), induction of labor (OR 5.300, 95% CI 4.514 to 6.224) and abnormal characters of amniotic fluid (OR 3.126, 95% CI 2.708 to 3.608). A risk scoring system (six grades) was established based on those factors which showed high discriminative power. The rate of EmCS was 1.30%, 2.57%, 5.83%, 13.94%, 21.75% and 39.71% in grades 1, 2, 3, 4, 5 and 6, respectively. The area under the curve of the risk scoring system was 0.787, indicating that the regression model of the risk factors had a good predictive ability.
An effective risk scoring system has been developed to quantitatively assess the risk of EmCS based on measurable maternal and fetal factors. The system is simple, easy to operate and has good repeatability in clinical practice.
分析影响急诊剖宫产(EmCS)的母胎因素,并建立风险评分系统以定量预测EmCS风险。
本研究共纳入10295名孕妇。分析母胎因素对EmCS风险的影响。
991例(9.63%)阴道分娩失败的产妇接受了EmCS。EmCS的两个主要原因是胎儿窘迫(67.21%)和胎位异常(14.93%)。正常阴道分娩(NVD)组和EmCS组在17个母胎因素上存在显著差异(所有p<0.05)。单因素和多因素回归分析显示,9个母婴因素为独立危险因素(所有p<0.05)。主要因素为羊水过少(OR 6.867,95%CI 4.442至10.618)、初产妇(OR 4.336,95%CI 3.074至6.115)、引产(OR 5.300,95%CI 4.514至6.224)和羊水性状异常(OR 3.126,95%CI 2.708至3.608)。基于这些具有高鉴别力的因素建立了一个风险评分系统(六个等级)。1、2、3、4、5和6级的EmCS发生率分别为1.30%、2.57%、5.83%、13.94%、21.75%和39.71%。风险评分系统的曲线下面积为0.787,表明危险因素回归模型具有良好的预测能力。
已开发出一种有效的风险评分系统,可基于可测量的母胎因素定量评估EmCS风险。该系统简单、易于操作,在临床实践中具有良好的重复性。