College of Chemistry and Chemical Engineering, Hunan University , Changsha 410082, Hunan, P. R. China.
Sino-German Joint Research Lab for Space Biomaterials and Translational Technology, School of Life Sciences, Northwestern Polytechnical University , Xi'an, Shaanxi 710072, P. R. China.
Langmuir. 2017 Dec 5;33(48):13861-13866. doi: 10.1021/acs.langmuir.7b03431. Epub 2017 Nov 16.
For designing water-soluble responsive materials, utilizing crown ethers as main building blocks has been rarely explored in contrast to their linear poly(ethylene glycol) counterparts. In the current study, we report the robust thermoresponsive properties of the benzo-21-crown-7 (B21C7) family with lower critical solution temperature (LCST) and upper critical solution temperature (UCST) behavior. Different substituent groups on the benzene ring exhibit significant effects on water solubility and thermoresponsiveness. B21C7 and its cyano derivative display LCST phenomena, while B21C7-based carboxylic acid derivative presents UCST followed by LCST phase behavior. Supramolecular interactions with KCl provide an additional tuning approach for this crown ether system. These results demonstrate that B21C7s can serve as an easily accessible toolbox to develop new thermosensitive systems and prepare thermally responsive materials.
用于设计水溶性响应性材料时，与线性聚（乙二醇）类似物相比，利用冠醚作为主要结构单元的情况很少被探索。在本研究中，我们报道了苯并-21-冠-7（B21C7）家族的强热敏性质，其具有较低临界溶液温度（LCST）和上临界溶液温度（UCST）行为。苯环上的不同取代基对水溶性和热敏性有显著影响。B21C7 和其氰基衍生物表现出 LCST 现象，而基于 B21C7 的羧酸衍生物则表现出 UCST 后跟随 LCST 相行为。与 KCl 的超分子相互作用为该冠醚体系提供了另一种调谐方法。这些结果表明，B21C7 可以作为一种易于获得的工具包，用于开发新的热敏性系统和制备热敏响应材料。
