Carmona-Fonseca Jaime, Arango Eliana M
Grupo Salud y Comunidad-César Uribe Piedrahíta, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
J Vector Borne Dis. 2017 Jul-Sep;54(3):201-206. doi: 10.4103/0972-9062.217610.
Though asymptomatic plasmodial infection (API) is well known phenomenon and play an important role in different populations and malaria transmission settings, it has received less attention in malaria intervention strategies. This review was aimed to estimate the prevalence of API in pregnant women across the world. The bibliography records relevant to the study were searched on PubMed and Lilacs, till August 15, 2016, without restriction of language. A total of 78 references were identified, of which 29 met the inclusion criteria. The study of the identified reports revealed that the mean prevalence of API in pregnant women was 10.8% (3382/31186), with wide variation among countries and transmission settings. The reports showed that APIs are very common even in low malaria transmission areas, and most of the APIs are due to submicroscopic plasmodial infection (SPI). More sensitive diagnostic tools are required to address API and SPI in such areas. Every malaria endemic region/country should carry out systematic studies for accurate estimation of frequency for both these events (API and SPI) in different populations for planning appropriate intervention measures.
尽管无症状疟原虫感染（API）是一种广为人知的现象，并且在不同人群和疟疾传播环境中发挥着重要作用，但它在疟疾干预策略中受到的关注较少。本综述旨在估计全球孕妇中API的流行率。截至2016年8月15日，在PubMed和Lilacs上检索了与该研究相关的文献记录，不受语言限制。共识别出78篇参考文献，其中29篇符合纳入标准。对已识别报告的研究表明，孕妇中API的平均流行率为10.8%（3382/31186），各国和传播环境之间存在很大差异。报告显示，即使在低疟疾传播地区，API也非常普遍，并且大多数API是由亚显微疟原虫感染（SPI）引起的。需要更敏感的诊断工具来应对此类地区的API和SPI。每个疟疾流行地区/国家都应开展系统研究，以便准确估计不同人群中这两种情况（API和SPI）的发生频率，从而规划适当的干预措施。
