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头颈部肿瘤临床实践指南（2017 年）

SEOM clinical guideline in nasopharynx cancer (2017).

机构信息

Servicio de Oncología Médica, Hospital La Fe de Valencia, Valencia, Spain.

Servicio de Oncología Médica - IIBSP, Hospital Sant Pau, Barcelona, Spain.

出版信息

Clin Transl Oncol. 2018 Jan;20(1):84-88. doi: 10.1007/s12094-017-1777-0. Epub 2017 Nov 2.

DOI:10.1007/s12094-017-1777-0
PMID:29098554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5785612/
Abstract

Nasopharyngeal carcinoma (NPC) is distinct from other cancers of the head and neck in biology, epidemiology, histology, natural history, and response to treatment. Radiation therapy is an essential component of curative-intent of non-disseminated disease and the association of chemotherapy improves the rates of survival. In the case of metastatic disease stages, treatment requires platinum/gemcitabine-based chemotherapy and patients may achieve a long survival time.

摘要

鼻咽癌（NPC）在生物学、流行病学、组织学、自然史和对治疗的反应方面与头颈部的其他癌症不同。放射治疗是治疗非扩散性疾病的重要组成部分，联合化疗可提高生存率。对于转移性疾病阶段，治疗需要基于铂类/吉西他滨的化疗，患者可能实现较长的生存时间。

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本文引用的文献

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2
Induction chemotherapy plus concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: a phase 3, multicentre, randomised controlled trial.诱导化疗加同期放化疗对比单纯同期放化疗治疗局部晚期鼻咽癌：一项 3 期、多中心、随机对照临床试验。
Lancet Oncol. 2016 Nov;17(11):1509-1520. doi: 10.1016/S1470-2045(16)30410-7. Epub 2016 Sep 27.
3
Gemcitabine plus cisplatin versus fluorouracil plus cisplatin in recurrent or metastatic nasopharyngeal carcinoma: a multicentre, randomised, open-label, phase 3 trial.吉西他滨联合顺铂对比氟尿嘧啶联合顺铂治疗复发或转移性鼻咽癌的多中心、随机、开放标签、III 期临床试验。
Lancet. 2016 Oct 15;388(10054):1883-1892. doi: 10.1016/S0140-6736(16)31388-5. Epub 2016 Aug 23.
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Radiother Oncol. 2014 Mar;110(3):377-84. doi: 10.1016/j.radonc.2014.02.003. Epub 2014 Mar 11.
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