Mori E, Yamadori A, Furumoto M
Neurology Service, Hyogo Brain and Heart Center, Himeji, Japan.
Neurology. 1989 Jan;39(1):51-4. doi: 10.1212/wnl.39.1.51.
We describe an autopsied case in which a circumscribed lesion involving the left precentral gyrus caused mild but lasting Broca's aphasia. The patient developed nonfluent speech and writing disturbances (consistent with mild Broca's aphasia) following malignant lymphoma of the brain. After subtotal resection of the tumor and whole brain irradiation, his language disturbances continued without remarkable change for 3 years until his death. A neuropathologic study indicated that the lesion responsible for the patient's aphasia was restricted to the lower one-third of the precentral gyrus in the left hemisphere. As for the relationship between the left precentral gyrus and Broca's aphasia and its allied syndrome (ie, aphemia), we concluded that in Broca's aphasia the lower part of the precentral gyrus plays a more important role than previously assumed.
我们描述了一例尸检病例，其中累及左中央前回的局限性病变导致了轻度但持续的布罗卡失语症。该患者在患脑恶性淋巴瘤后出现了非流畅性言语和书写障碍（符合轻度布罗卡失语症）。在肿瘤次全切除和全脑照射后，他的语言障碍持续存在，3年内无明显变化，直至死亡。神经病理学研究表明，导致患者失语症的病变局限于左半球中央前回的下三分之一。至于左中央前回与布罗卡失语症及其相关综合征（即运动性失语症）之间的关系，我们得出结论，在布罗卡失语症中，中央前回下部所起的作用比之前认为的更为重要。
