Yang Yufei, Xiang ShengQi, Liu Xiaodan, Pei Xiaojing, Wu Pengzhi, Gong Qingguo, Li Na, Baldus Marc, Wang Shenlin
College of Chemistry and Molecular Engineering, Beijing, China.
Chem Commun (Camb). 2017 Nov 30;53(96):12886-12889. doi: 10.1039/c7cc07483b.
We report a novel proton-detected MAS solid-state NMR strategy based on N-N proton assisted recoupling to detect the inter-nucleotide NHN hydrogen bonds within the Watson-Crick base pairs of micro-crystallized dimeric RNA and to confirm the kissing-loop structure. This would contribute to advances in the structural determination of RNA using solid-state NMR.
我们报告了一种基于N-N质子辅助重新耦合的新型质子检测MAS固态核磁共振策略，用于检测微晶二聚体RNA的沃森-克里克碱基对中的核苷酸间NHN氢键，并确认亲吻环结构。这将有助于推动利用固态核磁共振进行RNA结构测定的进展。
