Larsen M, Kjer B, Bendtson I, Dalgaard P, Lund-Andersen H
Department of Ophthalmology, Gentofte Hospital, Hellerup, Denmark.
Arch Ophthalmol. 1989 Jan;107(1):59-62. doi: 10.1001/archopht.1989.01070010061028.
The correlation of blue-green lens fluorescence to the metabolic control of insulin-dependent diabetes mellitus was studied in 36 patients in whom the level of glycosylated hemoglobin A1c (HbA1c) had been followed from the onset of diabetes. Good metabolic control (22 patients, all with mean HbA1c levels, less than 7.0% and, thus, low blood glucose concentrations) was associated with less lens fluorescence and a higher lens transmittance than poor metabolic control (14 patients, all with mean HbA1c levels, greater than 9.7%). It appears that in diabetes, an increase in lens fluorescence and a decrease in lens transmittance are delayed by good metabolic control, and that the determination of lens fluorescence provides information about the long-term control of diabetes.
对36例胰岛素依赖型糖尿病患者进行了研究，这些患者自糖尿病发病起就一直监测糖化血红蛋白A1c（HbA1c）水平，以探讨蓝绿色晶状体荧光与胰岛素依赖型糖尿病代谢控制之间的相关性。代谢控制良好的患者（22例，所有患者的平均HbA1c水平均低于7.0%，因此血糖浓度较低）与代谢控制不佳的患者（14例，所有患者的平均HbA1c水平均高于9.7%）相比，晶状体荧光较少，晶状体透光率较高。看来，在糖尿病中，良好的代谢控制可延缓晶状体荧光增加和晶状体透光率降低，并且晶状体荧光测定可为糖尿病的长期控制提供信息。
