School of Medicine and Public Health, University of Newcastle, Hunter Medical Research Institute, NSW, Australia; Neuroscience Research Australia (NeuRA), Sydney, NSW, Australia; Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, Australia; Centre for Pain, Health and Lifestyle, Australia.
Research Institute for Primary Care & Health Sciences, Keele University, Keele, Staffordshire ST5 5BG, UK.
Best Pract Res Clin Rheumatol. 2016 Dec;30(6):1074-1083. doi: 10.1016/j.berh.2017.04.001. Epub 2017 May 5.
In recent years, there has been increasing interest in studying causal mechanisms in the development and treatment of back pain. The aim of this article is to provide an overview of our current understanding of causal mechanisms in the field. In the first section, we introduce key concepts and terminology. In the second section, we provide a brief synopsis of systematic reviews of mechanism studies relevant to the clinical course and treatment of back pain. In the third section, we reflect on the findings of our review to explain how understanding causal mechanisms can inform clinical practice and the implementation of best practice. In the final sections, we introduce contemporary methodological advances, highlight the key assumptions of these methods, and discuss future directions to advance the quality of mechanism-related studies in the back pain field.
近年来，人们对研究背疼的发展和治疗中的因果机制越来越感兴趣。本文旨在概述我们目前对该领域因果机制的理解。在第一节中，我们介绍了关键概念和术语。在第二节中，我们简要总结了与背疼的临床病程和治疗相关的机制研究的系统综述。在第三节中，我们反思了我们的综述结果，以解释理解因果机制如何为临床实践和最佳实践的实施提供信息。在最后几节中，我们介绍了当代方法学的进展，强调了这些方法的关键假设，并讨论了未来的方向，以提高背疼领域与机制相关研究的质量。
