Sajid Irfan, Ahmad Saara, Emad Shaista, Batool Zehra, Khaliq Saima, Anis Lubna, Tabassum Saiqa, Madiha Syeda, Liaquat Laraib, Sadir Sadia, Perveen Tahira, Haider Saida
Department of Biochemistry, Federal Urdu University of Arts, Science & Technology, Gulshan-e-Iqbal Campus, Karachi, Pakistan.
Department of Biological and Biomedical Sciences, The Aga Khan University, Karachi, Pakistan.
Pak J Pharm Sci. 2017 Sep;30(5(Supplementary)):1957-1963.
Energy drinks enhance physical endurance and cognitive ability. The ingredients present in these drinks are considered as ergogenic and have memory boosting effects. In the present study effects of taurine administration for one week was monitored on physical exercise and memory performance in rats. Animals were divided into two groups namely control and test. Taurine was injected intraperitoneally to the test group at the dose of 100mg/kg. After one week of treatment rats were subjected to physical exercise and memory task. Results of this study revealed that rats injected with taurine for one week exhibited improved muscular strength as well as enhanced memory performance in Morris water maze and elevated plus maze. Biomarker of lipid peroxidation was significantly reduced in brain and plasma of test animals. Taurine administration also resulted in higher levels of corticosterone in this study. The results highlight the significance of taurine ingestion in energy demanding and challenging situations in athletes and young subjects.
能量饮料可增强身体耐力和认知能力。这些饮料中的成分被认为具有促力作用,并有增强记忆力的效果。在本研究中,监测了大鼠连续一周给予牛磺酸对其体育锻炼和记忆表现的影响。动物被分为两组,即对照组和试验组。以100mg/kg的剂量向试验组腹腔注射牛磺酸。治疗一周后,让大鼠进行体育锻炼和记忆任务。本研究结果显示,连续一周注射牛磺酸的大鼠在莫里斯水迷宫和高架十字迷宫中表现出肌肉力量增强以及记忆表现提高。试验动物大脑和血浆中的脂质过氧化生物标志物显著降低。在本研究中,给予牛磺酸还导致皮质酮水平升高。这些结果凸显了在运动员和年轻受试者面临需要能量和具有挑战性的情况下摄入牛磺酸的重要性。