Alpert B, Colosi T, von Fraunhofer J A, Seligson D
Department of Oral and Maxillofacial Surgery, University of Louisville School of Dentistry, KY 40292.
J Oral Maxillofac Surg. 1989 Jan;47(1):46-9. doi: 10.1016/0278-2391(89)90123-7.
Gentamicin-PMMA beads were placed in maxillofacial wounds of ten dogs, and gentamicin levels from wound drain sites, serum, and urine were measured by radioimmunoassay. The results indicate extremely high wound and modest urine levels (which decrease exponentially) concurrently with negligible serum levels of gentamicin. The results of this study of a highly vascularized area were similar to other studies in which beads were placed in avascular areas.
将庆大霉素 - 聚甲基丙烯酸甲酯珠粒置于10只狗的颌面伤口中，通过放射免疫测定法测量伤口引流部位、血清和尿液中的庆大霉素水平。结果表明，伤口处庆大霉素水平极高，尿液中庆大霉素水平适中（呈指数下降），而血清中庆大霉素水平可忽略不计。这项针对高度血管化区域的研究结果与其他将珠粒置于无血管区域的研究结果相似。
