Crépy C, Brochériou C, Sabbah C
Rev Stomatol Chir Maxillofac. 1979;80(5):242-5.
Lupus is a particularly polymorphic disease involving all medical disciplines and inciting the publication of an increasing number of papers. The two clinical types of lupus (acute disseminated lupus erythematosus and chronic lupus) have, until recently, led to doubts as to the unified nature of the disease. Grouping the symptoms and the results of their investigation in a computer has shown that there are 14 elements which occur most frequently, though there is no absolute pathognomonic sign of the disease. Oropharyngeal ulcerations, without being typical, are on of the fundamental signs and were found in 10% of cases of chronic lupus. The Gougerot-Sjögren syndrome is sometimes found, but it is not one of the fundamental signs : its existence, however, has enabled progress to be made during research into the auto-immune physiopathology of lupus disease.
狼疮是一种极为多态性的疾病，涉及所有医学学科，并促使越来越多的论文发表。直到最近，狼疮的两种临床类型（急性播散性红斑狼疮和慢性狼疮）还让人对该疾病的统一性产生怀疑。将症状及其调查结果输入计算机进行归类分析后发现，有14种要素出现的频率最高，不过该疾病并没有绝对的特征性体征。口腔咽喉溃疡虽不典型，但却是基本体征之一，在10%的慢性狼疮病例中可以发现。有时会发现古热罗-舍格伦综合征，但它并非基本体征之一：然而，它的存在推动了狼疮疾病自身免疫生理病理学研究的进展。
