Jonsson R, Heyden G, Westberg N G, Nyberg G
J Rheumatol. 1984 Feb;11(1):38-42.
The oral mucosa was investigated in 51 patients with systemic lupus erythematosus (SLE). Lesions were seen in 23 patients (45%). Most lesions were of discoid type or erythemas; only 3 were seen in 23 patients (45%). Most lesions were of discoid type or erythemas; only 3 were ulcerations. The hard palate, buccal mucosa and vermilion border were the most frequent sites of involvement. The overall prevalence was not related to disease activity, but discoid lesions and ulcerations were only seen in patients with active disease. Histopathological investigation showed liquefactive degeneration in 6 biopsies of 10 lesions. Immunofluorescence examination was positive in all cases.
对51例系统性红斑狼疮（SLE）患者的口腔黏膜进行了研究。23例患者（45%）出现了病变。大多数病变为盘状或红斑型；23例患者中仅3例（45%）出现溃疡。硬腭、颊黏膜和唇红缘是最常受累的部位。总体患病率与疾病活动度无关，但盘状病变和溃疡仅见于疾病活动期的患者。组织病理学检查显示，10个病变中的6个活检标本出现液化性变性。所有病例的免疫荧光检查均为阳性。
