水生生物对农药三氯生的毒性评估及降解研究。
Toxicity assessment of pesticide triclosan by aquatic organisms and degradation studies.
机构信息
Polatlı Faculty of Science & Arts, Gazi University, 06900, Polatlı, Ankara, Turkey; Health Services Vocational School, Gazi University, 06830, Gölbaşı, Ankara, Turkey; Life Sciences Application and Research Center, Gazi University, 06830, Gölbaşı, Ankara, Turkey.
Life Sciences Application and Research Center, Gazi University, 06830, Gölbaşı, Ankara, Turkey; Department of Medical Biology and Genetics, Faculty of Medicine, Gazi University, 06500, Ankara, Turkey.
出版信息
Regul Toxicol Pharmacol. 2017 Dec;91:208-215. doi: 10.1016/j.yrtph.2017.10.030. Epub 2017 Oct 27.
Triclosan is considered as an important contaminant and is widely used in personal care products as an antimicrobial agent. This study demonstrates the biodegradation of triclosan by two freshwater microalgae and the acute toxicity of triclosan and 2,4-dichlorophenol. The effects of culture media and light on biodegradation of triclosan and the changing morphology of microalgae were systematically studied. Geitlerinema sp. and Chlorella sp. degraded 82.10% and 92.83% of 3.99 mg/L of triclosan at 10 days, respectively. The microalgal growth inhibition assay confirmed absence of toxic effects of triclosan on Chlorella sp., even at higher concentration (50 mg/L) after 72 h exposure. HPLC analysis showed that 2,4-dichlorophenol was produced as degradation product of triclosan by Geitlerinema sp. and Chlorella sp. This study proved to be beneficial to understand biodegradation and acute toxicity of triclosan by microalgae in order to provide aquatic environmental protection.
三氯生被认为是一种重要的污染物，广泛应用于个人护理产品中作为一种抗菌剂。本研究通过两种淡水微藻展示了三氯生的生物降解作用，以及三氯生和 2,4-二氯苯酚的急性毒性。系统研究了培养基和光照对三氯生生物降解和微藻形态变化的影响。Geitlerinema sp. 和 Chlorella sp. 在 10 天内分别降解了 3.99mg/L 的三氯生 82.10%和 92.83%。微藻生长抑制试验证实，三氯生对 Chlorella sp. 没有毒性作用，即使在 72 小时暴露于更高浓度（50mg/L）时也没有毒性作用。HPLC 分析表明，2,4-二氯苯酚是 Geitlerinema sp. 和 Chlorella sp. 降解三氯生的产物。本研究有助于了解微藻对三氯生的生物降解和急性毒性，为水生环境保护提供了依据。
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