Institute of Applied Radiation Chemistry, Faculty of Chemistry, Lodz University of Technology, Wroblewskiego 15, 93-590 Lodz, Poland.
Int J Mol Sci. 2019 May 20;20(10):2492. doi: 10.3390/ijms20102492.
In this review, the effect of pharmaceuticals (PHRs) and personal care products (PCPs) on microalgal growth and metabolism is reported. Concentrations of various PHRs and PCPs that cause inhibition and toxicity to growths of different microalgal strains are summarized and compared. The effect of PHRs and PCPs on microalgal metabolism (oxidative stress, enzyme activity, pigments, proteins, lipids, carbohydrates, toxins), as well as on the cellular morphology, is discussed. Literature data concerning the removal of PHRs and PCPs from wastewaters by living microalgal cultures, with the emphasis on microalgal growth, are gathered and discussed. The potential of simultaneously bioremediating PHRs/PCPs-containing wastewaters and cultivating microalgae for biomass production in a single process is considered. In the light of reviewed data, the feasibility of post-bioremediation microalgal biomass is discussed in terms of its contamination, biosafety and further usage for production of value-added biomolecules (pigments, lipids, proteins) and biomass as a whole.
本文综述了药品（PHRs）和个人护理产品（PCPs）对微藻生长和代谢的影响。总结和比较了不同 PHRs 和 PCPs 浓度对不同微藻菌株生长的抑制和毒性作用。讨论了 PHRs 和 PCPs 对微藻代谢（氧化应激、酶活性、色素、蛋白质、脂质、碳水化合物、毒素）以及细胞形态的影响。收集和讨论了有关利用活体微藻培养物去除废水中 PHRs 和 PCPs 的文献数据，重点是微藻生长。考虑了在单一过程中同时生物修复含 PHRs/PCPs 的废水和培养微藻用于生物质生产的潜力。根据综述数据，从污染、生物安全性以及进一步用于生产增值生物分子（色素、脂质、蛋白质）和整个生物质的角度讨论了生物修复后微藻生物质的可行性。
