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采用非接触式钇铝石榴石激光对肺部结节(硬币样)病变进行局部切除。

Local excision of pulmonary nodular (coin) lesion with noncontact yttrium-aluminum-garnet laser.

作者信息

Moghissi K

机构信息

Humberside Cardiothoracic Surgical Centre, Castle Hill Hospital, Cottingham, England.

出版信息

J Thorac Cardiovasc Surg. 1989 Jan;97(1):147-51.

PMID:2911192
Abstract

Local excision of pulmonary nodular lesions with the noncontact mode of the neodymium: yttrium-aluminum-garnet laser was done in 14 patients. This was achieved through a conventional limited thoracotomy and then by evaporation/fulguration of 0.5 to 1 cm of the healthy parenchyma surrounding the lesion, which produced a bloodless incision. In 10 patients the lesion was a primary (N = 7) or secondary (N = 3) malignant tumor. The remaining four had a benign nodule. Preoperative radiology has demonstrated a solitary nodule in all 14 patients, but at operation in four patients (three with benign and one with malignant disease) there were two nodules. In each of these four patients the smaller nodule was evaporated entirely, without excision of normal pulmonary tissue. There were no hospital deaths or postoperative complications. One patient died 8 months postoperatively (carcinomatosis); the other 13 remain alive and well between 2 and 25 months after treatment. We believe that local excision of nodular pulmonary lesions with the laser should be considered whenever possible, particularly in high-risk patients, those with limited respiratory function, and in the elderly.

摘要

对14例患者采用钕:钇铝石榴石激光非接触模式对肺部结节性病变进行局部切除。这是通过传统的有限开胸术,然后对病变周围0.5至1厘米的健康实质组织进行汽化/电凝来实现的,这样可形成无血切口。10例患者的病变为原发性(7例)或继发性(3例)恶性肿瘤。其余4例为良性结节。术前影像学检查显示所有14例患者均为孤立性结节,但术中4例患者(3例良性疾病和1例恶性疾病)发现有两个结节。在这4例患者中,较小的结节均被完全汽化,未切除正常肺组织。无医院死亡病例或术后并发症。1例患者术后8个月死于癌转移;其他13例患者在治疗后2至25个月期间仍存活且状况良好。我们认为,只要有可能,尤其是对于高危患者、呼吸功能受限患者以及老年人,应考虑采用激光对肺部结节性病变进行局部切除。

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