职业暴露与西班牙裔/拉丁裔人群的代谢综合征：西班牙裔社区健康研究/拉丁裔研究（HCHS/SOL）的横断面研究结果。
Occupational Exposures and Metabolic Syndrome Among Hispanics/Latinos: Cross-Sectional Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
机构信息
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois (Ms Bulka, Drs Persky, Argos); Institute for Minority Health Research, Section of General Internal Medicine, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois (Ms Bulka, Drs Daviglus, Durazo-Arvizu); National Heart, Lung, and Blood Institute at the National Institutes of Health, Bethesda, Maryland (Dr Avilés-Santa); Department of Psychology, San Diego State University, San Diego, California (Dr Gallo); Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York City, New York (Dr Hosgood III); Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, Florida (Dr Singer); Division of Health Promotion and Behavioral Science, San Diego State University, San Diego, California (Dr Talavera); Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota (Dr Thyagarajan); and Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (Dr Zeng).
出版信息
J Occup Environ Med. 2017 Nov;59(11):1047-1055. doi: 10.1097/JOM.0000000000001115.
OBJECTIVE
We assessed the cross-sectional relationships of self-reported current occupational exposures to solvents, metals, and pesticides with metabolic syndrome and its components among 7127 participants in the Hispanic Community Health Study/Study of Latinos.
METHODS
Metabolic syndrome was defined as a clustering of abdominal obesity, high triglycerides, low high-density lipoprotein cholesterol, high blood pressure, and/or high fasting glucose. Regression models that incorporated inverse probability of exposure weighting were used to estimate prevalence ratios.
RESULTS
Solvent exposure was associated with a 32% higher prevalence of high blood pressure (95% confidence interval: 1.09 to 1.60) than participants not reporting exposure. No associations were observed for occupational exposures with abdominal obesity, high triglycerides, low high-density lipoprotein, or metabolic syndrome.
CONCLUSION
Our findings suggest that solvent exposure may be an important occupational risk factor for high blood pressure among Hispanics/Latinos in the United States.
目的
我们评估了 7127 名西班牙裔社区健康研究/拉丁裔研究参与者中报告的当前职业暴露于溶剂、金属和农药与代谢综合征及其成分的横断面关系。
方法
代谢综合征的定义为腹部肥胖、高甘油三酯、低高密度脂蛋白胆固醇、高血压和/或高空腹血糖的聚集。采用纳入暴露反概率加权的回归模型来估计患病率比。
结果
与未报告暴露的参与者相比，溶剂暴露与高血压的患病率高出 32%（95%置信区间：1.09 至 1.60）。职业暴露与腹部肥胖、高甘油三酯、低高密度脂蛋白或代谢综合征之间没有关联。
结论
我们的研究结果表明，在美国的西班牙裔/拉丁裔人群中，溶剂暴露可能是高血压的一个重要职业危险因素。
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