伊朗胃食管反流病患者中细胞毒素相关基因的患病率。
Prevalence of cytotoxin-associated genes of among Iranian GERD patients.
作者信息
Shavalipour Aref, Malekpour Habib, Dabiri Hossein, Kazemian Hossein, Zojaji Homayon, Bahroudi Mahboube
机构信息
Department of Medical Microbiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases Shahid Beheshti University Medical Sciences, Tehran, Iran.
出版信息
Gastroenterol Hepatol Bed Bench. 2017 Summer;10(3):178-183.
AIM
Since the impact of and its virulence is not clear in GERD, this study aimed to evaluate the prevalence of and gens of among Iranian GERD patients.
BACKGROUND
Gastroesophageal reflux disease (GERD) is defined as a condition of reflux the stomach juice by low pH causes tissue damage. may or may not influence the GERD; however, it is unclear.
METHODS
This study was a case-control study performed on patients with GERD who underwent upper gastrointestinal endoscopy at Taleghani Hospital of Tehran, Iran. Prevalence of H. pylori and presence of the cag and genes in GERD and control group was investigated.
RESULTS
was detected in 54% and 62% of GERD and control groups respectively. Prevalence of gene among GERD patients was 44.4% whereas among the control group it was 87%. Prevalence of the among GERD patients and control group was 44.4% and 64% respectively. Coexistence of and in GERD patients was 25.7% and in the control patients it was 54.8%.
CONCLUSION
We did not find correlation between existence in GERD patients in comparison to the control group. Similar to other Asian studies, the presence of the c in control group was more than GERD patients significantly. The co-existence of and was also more in control group significantly.
目的
由于[具体内容]及其毒力在胃食管反流病（GERD）中的影响尚不清楚，本研究旨在评估伊朗GERD患者中[具体内容]及其[具体基因]的流行情况。
背景
胃食管反流病（GERD）被定义为胃酸反流导致组织损伤的一种病症。[具体内容]可能会也可能不会影响GERD；然而，目前尚不清楚。
方法
本研究是一项病例对照研究，对在伊朗德黑兰塔莱加尼医院接受上消化道内镜检查的GERD患者进行。调查了GERD组和对照组中幽门螺杆菌（H. pylori）的流行情况以及cag[具体基因]和[具体基因]的存在情况。
结果
GERD组和对照组中分别有54%和62%检测到[具体内容]。GERD患者中[具体基因]的流行率为44.4%，而对照组中为87%。GERD患者和对照组中[具体基因]的流行率分别为44.4%和64%。GERD患者中[具体内容]和[具体基因]共存的比例为25.7%，对照组患者中为54.8%。
结论
与对照组相比，我们未发现GERD患者中[具体内容]的存在与之存在相关性。与其他亚洲研究类似，对照组中[具体基因]的存在显著多于GERD患者。对照组中[具体内容]和[具体基因]的共存也显著更多。
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