Centre for Ecology and Evolution in Microbial Model Systems, Linnaeus University, SE-391 82 Kalmar, Sweden; Department of Biology, Carleton University, Ottawa, ON K1S 5B6, Canada.
Centre for Ecology and Evolution in Microbial Model Systems, Linnaeus University, SE-391 82 Kalmar, Sweden.
Curr Opin Virol. 2018 Feb;28:26-36. doi: 10.1016/j.coviro.2017.10.006. Epub 2017 Nov 6.
Low pathogenic influenza A virus (LPIAV) prevalence and subtype distribution differs between and across bird taxa. A crucial factor in the epidemiology of these viruses and virus subtypes is the ability to transmit between and within different host taxa and individuals. Successful viral transmission depends on availability of susceptible hosts and exposure of host to virus. Exposure to viruses and susceptibility to virus infection and/or disease are shaped by both host and virus traits. In this review we have identified key host and virus traits that can affect LPIAV transmission, both in terms of exposure and susceptibility. Furthermore we highlight current challenges in assessment of these traits and identify methodological considerations for future studies.
低致病性甲型流感病毒（LPIAV）在不同鸟类分类群之间的流行情况和亚型分布存在差异。这些病毒和病毒亚型在流行病学中的一个关键因素是在不同宿主分类群和个体之间传播的能力。病毒的成功传播取决于易感宿主的存在以及宿主与病毒的接触。宿主对病毒的暴露和易感性取决于宿主和病毒的特征。在这篇综述中，我们确定了关键的宿主和病毒特征，这些特征可以影响 LPIAV 的传播，包括暴露和易感性。此外，我们还强调了评估这些特征所面临的当前挑战，并确定了未来研究的方法学考虑因素。
