Olsen Björn, Munster Vincent J, Wallensten Anders, Waldenström Jonas, Osterhaus Albert D M E, Fouchier Ron A M
Department of Infectious Diseases, Umeå University, SE-90187 Umeå, Sweden.
Science. 2006 Apr 21;312(5772):384-8. doi: 10.1126/science.1122438.
The outbreak of highly pathogenic avian influenza of the H5N1 subtype in Asia, which has subsequently spread to Russia, the Middle East, Europe, and Africa, has put increased focus on the role of wild birds in the persistence of influenza viruses. The ecology, epidemiology, genetics, and evolution of pathogens cannot be fully understood without taking into account the ecology of their hosts. Here, we review our current knowledge on global patterns of influenza virus infections in wild birds, discuss these patterns in the context of host ecology and in particular birds' behavior, and identify some important gaps in our current knowledge.
H5N1亚型高致病性禽流感在亚洲爆发，随后蔓延至俄罗斯、中东、欧洲和非洲，这使得人们更加关注野生鸟类在流感病毒持续存在中的作用。如果不考虑病原体宿主的生态，就无法全面理解病原体的生态、流行病学、遗传学和进化。在此，我们回顾了目前关于野生鸟类流感病毒感染全球模式的知识，在宿主生态尤其是鸟类行为的背景下讨论了这些模式，并指出了我们目前知识中的一些重要空白。
