Elnady Hala Gouda, Abdel Samie Ola M, Saleh Maysa Tawhid, Sherif Lobna S, Abdalmoneam Naglaa, Kholoussi Naglaa M, Kholoussi Shams M, El-Taweel Ahmed N
Medical Division, Child Health Department, National Research Centre, Cairo, Egypt.
Paediatrics Department, Faculty of Medicine for Girls, Al-Zahraa University Hospital, Cairo, Egypt.
Prz Gastroenterol. 2017;12(3):175-180. doi: 10.5114/pg.2017.70469. Epub 2017 Sep 30.
Rotavirus gastroenteritis is an important public health problem all over the world, causing a notable economic burden in both developing and developed countries.
To explore the relationship between blood group typing, rotavirus gastroenteritis, and its severity in Egyptian children.
A cross sectional case control study was conducted on 231 cases of acute gastroenteritis attending the outpatient clinic of Al-Zahraa University Hospital. Full history taking, clinical examination, and clinical data collection were done. Blood samples were collected for an ABO grouping. Stool samples were tested for viral gastroenteritis agents.
Rota positive cases of GE were significantly more prevalent among cases with blood group A ( < 0.05) and significantly less among cases with blood group B ( < 0.05). The rate of hospitalisation was highly significantly greater among cases with group A ( < 0.005), and significantly lower among cases with group AB and O ( < 0.05). As regards the degree of dehydration, moderate and severe cases were highly significant in groups A and O ( < 0.005). Rota-positive gastroenteritis showed significant positive correlations with indicators of severity such as hospitalisation, degree of dehydration, and duration of fever ( < 0.005).
Blood group A is highly associated with paediatric rotavirus gastroenteritis. This could highlight an important risk factor, which could play a significant role for the pathogenesis of rotavirus gastroenteritis and severity as well. Furthermore, more intervention care could be needed for blood group A paediatric patients, if gastroenteritis especially rotavirus affect this group to avoid comorbidities.
轮状病毒肠胃炎是全球重要的公共卫生问题，在发展中国家和发达国家都会造成显著的经济负担。
探讨埃及儿童的血型分型、轮状病毒肠胃炎及其严重程度之间的关系。
对扎赫拉大学医院门诊的231例急性肠胃炎病例进行了一项横断面病例对照研究。进行了全面的病史采集、临床检查和临床数据收集。采集血样进行ABO血型分组。检测粪便样本中的病毒性肠胃炎病原体。
肠胃炎轮状病毒阳性病例在A型血患者中显著更常见（<0.05），在B型血患者中显著更少（<0.05）。A型血患者的住院率显著更高（<0.005），AB型血和O型血患者的住院率显著更低（<0.05）。关于脱水程度，A组和O组的中度和重度病例差异极显著（<0.005）。轮状病毒阳性肠胃炎与住院、脱水程度和发热持续时间等严重程度指标呈显著正相关（<0.005）。
A型血与小儿轮状病毒肠胃炎高度相关。这可能凸显了一个重要的风险因素，其在轮状病毒肠胃炎的发病机制和严重程度方面可能发挥重要作用。此外，如果肠胃炎尤其是轮状病毒感染A型血的小儿患者，可能需要更多的干预护理以避免并发症。
