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2002年至2012年日本关东地区院外心脏骤停患者院前及院内管理与结局的变化:SOS-KANTO 2012研究

Changes in pre- and in-hospital management and outcomes for out-of-hospital cardiac arrest between 2002 and 2012 in Kanto, Japan: the SOS-KANTO 2012 Study.

出版信息

Acute Med Surg. 2015 Feb 17;2(4):225-233. doi: 10.1002/ams2.102. eCollection 2015 Oct.

Abstract

AIM

The current study compares pre- and in-hospital management and outcomes of out-of-hospital cardiac arrest cases between 2002 and 2012 in the Kanto region of Japan.

METHODS

We compared the data collected for the SOS-KANTO study project in 2002 and 2012. We included adult patients (aged >18 years) who experienced bystander-witnessed out-of-hospital cardiac arrest of cardiac etiology. The outcomes were as follows: proportion of favorable neurological outcomes at 1 month, bystander cardiopulmonary resuscitation provision, and pre- and postresuscitation treatment administration.

RESULTS

Of 4,171 patients (1,982 in SOS-KANTO in 2002 and 2,189 in 2012), the proportion of those with favorable neurological outcomes at 1 month (4.8% versus 9.0%,  < 0.001), and bystander cardiopulmonary resuscitation rates increased significantly between 2002 and 2012 (24.5% versus 38.9%,  < 0.001). Although none were documented in 2002, 118 cases (5.4%) of layperson use of an automated external defibrillator were recorded in 2012. Relative to 2002, use of an i.v. line to provide fluid was more frequently attempted and carried out successfully by emergency medical service providers in 2012. Among cases in which return of spontaneous circulation was achieved, more postresuscitation treatment was provided in 2012 (13.3% versus 43.8%,  < 0.001) relative to that provided in 2002.

CONCLUSIONS

Proportions of bystander cardiopulmonary resuscitation, layperson use of automated external defibrillator, provision of prehospital adrenaline and postresuscitation treatment, and favorable neurological outcomes at 1 month increased significantly over 10 years in the Kanto region of Japan.

摘要

目的

本研究比较了2002年至2012年日本关东地区院外心脏骤停病例的院前和院内管理及结局。

方法

我们比较了2002年和2012年为SOS-KANTO研究项目收集的数据。纳入了成年患者(年龄>18岁),这些患者经历了旁观者目击的心脏病因院外心脏骤停。结局如下:1个月时良好神经功能结局的比例、旁观者进行心肺复苏的情况以及复苏前后的治疗实施情况。

结果

在4171例患者中(2002年SOS-KANTO研究中有1982例,2012年有2189例),2002年至2012年期间,1个月时良好神经功能结局的比例显著增加(4.8%对9.0%,P<0.001),旁观者心肺复苏率也显著提高(24.5%对38.9%,P<0.001)。2002年无相关记录,但2012年有118例(5.4%)非专业人员使用自动体外除颤器的情况被记录。与2002年相比,2012年紧急医疗服务人员更频繁地尝试并成功使用静脉输液提供液体。在实现自主循环恢复的病例中,2012年相对于2002年给予了更多的复苏后治疗(13.3%对43.8%,P<0.001)。

结论

在日本关东地区,10年间旁观者心肺复苏、非专业人员使用自动体外除颤器、院前给予肾上腺素和复苏后治疗的比例以及1个月时良好神经功能结局的比例均显著增加。

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