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增材制造制备的晶格结构植入物的XCT骨特征分析

XCT bone characterization of lattice structured implants fabricated by additive manufacturing.

作者信息

Obaton A-F, Fain J, Djemaï M, Meinel D, Léonard F, Mahé E, Lécuelle B, Fouchet J-J, Bruno G

机构信息

LNE, Laboratoire commun de métrologie (LNE/Cnam), Laboratoire National de Métrologie et d'Essais (LNE), 1 rue Gaston Boissier, Paris 75015, France.

Z3Dlab, Parc Technologique, 26 Rue des Sablons, Montmagny 95360, France.

出版信息

Heliyon. 2017 Sep 18;3(8):e00374. doi: 10.1016/j.heliyon.2017.e00374. eCollection 2017 Aug.

DOI:10.1016/j.heliyon.2017.e00374
PMID:29124235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5669606/
Abstract

Several cylindrical specimens and dental implants, presenting diagonal lattice structures with different cell sizes (600, 900 and 1200 μm) were additively manufactured by selective laser melting process. Then they were implanted for two months in a sheep. After removal, they were studied by Archimedes' method as well as X-ray computed tomography in order to assess the penetration of bone into the lattice. We observed that the additive manufactured parts were geometrically conformed to the theoretical specifications. However, several particles were left adhering to the surface of the lattice, thereby partly or entirely obstructing the cells. Nevertheless, bone penetration was clearly visible. We conclude that the 900 μm lattice cell size is more favourable to bone penetration than the 1200 μm lattice cell size, as the bone penetration is 84% for 900 μm against 54% for 1200 μm cell structures. The lower bone penetration value for the 1200 μm lattice cell could possibly be attributed to the short residence time in the sheep. Our results lead to the conclusion that lattice implants additively manufactured by selective laser melting enable better bone integration.

摘要

通过选择性激光熔化工艺增材制造了几个圆柱形标本和牙科植入物，它们呈现出具有不同单元尺寸（600、900和1200μm）的对角晶格结构。然后将它们植入绵羊体内两个月。取出后，采用阿基米德法以及X射线计算机断层扫描对其进行研究，以评估骨向晶格中的渗透情况。我们观察到增材制造的部件在几何形状上符合理论规格。然而，有几个颗粒附着在晶格表面，从而部分或完全阻塞了单元。尽管如此，骨渗透情况仍清晰可见。我们得出结论，900μm的晶格单元尺寸比1200μm的晶格单元尺寸更有利于骨渗透，因为900μm的骨渗透率为84%，而1200μm单元结构的骨渗透率为54%。1200μm晶格单元较低的骨渗透值可能归因于在绵羊体内的停留时间较短。我们的结果得出结论，通过选择性激光熔化增材制造的晶格植入物能够实现更好的骨整合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/7925ea7ec8b8/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/9518ca82e16c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/c7be9173fed3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/2fb7745108ea/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/7d14a59ef641/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/b75ed31485e2/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/51695ef99869/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/b3ffae423754/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/3088b57abea7/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/f0946a2a79b9/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/33d808f56f68/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/fc53a29d6561/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/7925ea7ec8b8/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/9518ca82e16c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/c7be9173fed3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/2fb7745108ea/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/7d14a59ef641/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/b75ed31485e2/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/51695ef99869/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/b3ffae423754/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/3088b57abea7/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/f0946a2a79b9/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/33d808f56f68/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/fc53a29d6561/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d8b/5669606/7925ea7ec8b8/gr12.jpg

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