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当前在不同临床环境下心内科医生对稳定型冠心病患者的管理和治疗:一项前瞻性、观察性、全国性研究。

Current management and treatment of patients with stable coronary artery diseases presenting to cardiologists in different clinical contexts: A prospective, observational, nationwide study.

机构信息

1 Division of Cardiology, S. Giovanni Evangelista Hospital, Tivoli (Roma), Italy.

2 Division of Cardiology, Istituti Clinici Scientifici Maugeri, IRCCS, Veruno (Novara), Italy.

出版信息

Eur J Prev Cardiol. 2018 Jan;25(1):43-53. doi: 10.1177/2047487317740663. Epub 2017 Nov 10.

Abstract

Background Stable coronary artery disease (CAD) is a leading cause of mortality worldwide. Few studies document the complete sequence of investigation of the overall stable CAD population during outpatient visits or hospitalisation. Aim To obtain accurate and up-to-date information on current management of patients with stable CAD. Methods START (STable coronary Artery diseases RegisTry) was a prospective, observational, nationwide study aimed at evaluating the presentation, management, treatment and quality of life of stable CAD patients presenting to cardiologists during outpatient visits or discharged from cardiology wards. Results Over a 3-month period, 5070 consecutive patients were enrolled in 183 participating centres: 72% managed by a cardiologist during outpatient or day hospital visits and 28% discharged from cardiology wards. The vast majority of patients (87%) received a coronary angiography (86% of patients managed during outpatient visits and 90% during hospitalisation; p < 0.0001). Outpatients more frequently received optimal medical therapy (OMT; i.e. aspirin or thienopyridine, β-blockers and statins) compared to hospitalised patients (70.2% vs 67.1%; p = 0.03). A personalised diet was prescribed in 58% (60.5% in outpatients and 52.9% in those admitted to hospitals; p < 0.0001), physical activity programmes were suggested in 65% (69.4% and 54.3%; p < 0.0001) and smoking cessation was recommended in 71% of currently smoking patients (73.2% and 65.2%; p = 0.02). Conclusions In this large, contemporary registry, patients with stable CAD discharged from cardiology wards more commonly underwent diagnostic imaging procedures and less frequently received OMT or lifestyle modification programmes compared to patients manged by cardiologists during outpatient visits.

摘要

背景

稳定型冠状动脉疾病(CAD)是全球范围内导致死亡的主要原因。很少有研究记录整体稳定型 CAD 人群在门诊就诊或住院期间的完整检查过程。

目的

获得关于稳定型 CAD 患者当前管理的准确和最新信息。

方法

START(稳定型冠状动脉疾病注册研究)是一项前瞻性、观察性的全国性研究,旨在评估在门诊就诊或从心脏病病房出院的稳定型 CAD 患者的临床表现、管理、治疗和生活质量。

结果

在 3 个月的时间里,5070 名连续患者被纳入 183 个参与中心:72%由心脏病专家在门诊或日间病房就诊时管理,28%从心脏病病房出院。绝大多数患者(87%)接受了冠状动脉造影(86%的门诊就诊患者和 90%的住院患者接受了冠状动脉造影;p<0.0001)。与住院患者相比,门诊患者更频繁地接受最佳药物治疗(OMT;即阿司匹林或噻吩吡啶、β受体阻滞剂和他汀类药物)(70.2%对 67.1%;p=0.03)。58%的患者开了个性化饮食处方(门诊患者为 60.5%,住院患者为 52.9%;p<0.0001),65%的患者建议进行体育活动方案(69.4%和 54.3%;p<0.0001),71%的吸烟患者建议戒烟(73.2%和 65.2%;p=0.02)。

结论

在这项大型的当代注册研究中,与由心脏病专家在门诊就诊时管理的患者相比,从心脏病病房出院的稳定型 CAD 患者更常接受诊断性影像学检查,而较少接受 OMT 或生活方式改变方案。

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