Department of Cardiology, the Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China.
Division of Medical Affairs, the Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China.
Mil Med Res. 2019 Nov 25;6(1):36. doi: 10.1186/s40779-019-0226-5.
Stable angina is one of the most common clinical types of coronary artery disease (CAD) and associated with poor health-related quality of life (HRQL). However, few studies have evaluated the risk factors associated with HRQL in patients with newly diagnosed stable angina.
A cross-sectional survey was conducted with 342 consecutive outpatients with newly diagnosed stable angina from October 2017 to January 2018 at the Second Affiliated Hospital of Army Medical University, Chongqing, China. Eight dimensions of HRQL were evaluated via the 36-item Short-Form Health Survey, including physical functioning, role limitation due to physical problems, bodily pain, general health, vitality, social functioning, role limitation due to emotional problems, and mental health. Physical and mental component summaries were calculated. Multiple stepwise regression was performed to determine the factors associated with HRQL.
Patients who were older, were females, did not exercise, had lower educational levels, had lower monthly incomes, had smoking/drinking habits, and had diabetes, hypertension, or hyperlipemia showed lower physical HRQL scores, while those who were older with lower educational levels and lower monthly incomes showed lower mental HRQL scores. The results of the multiple stepwise regression analyses showed that physical and mental HRQL were positively correlated with exercise and monthly income and negatively associated with age. Patients with monthly income ≥5000 Yuan showed higher HRQL scores than those with monthly income < 5000 Yuan. Sleep quality and drinking were negatively associated with physical, but not mental HRQL.
Our findings indicated that exercise and personal income level, both modifiable factors, were positively associated with physical and mental HRQL. These findings could have implications for clinical suggestions and strategies to improve HRQL in patients with stable angina.
稳定型心绞痛是冠状动脉疾病（CAD）最常见的临床类型之一，与健康相关的生活质量（HRQL）较差相关。然而，很少有研究评估与新诊断的稳定型心绞痛患者 HRQL 相关的危险因素。
2017 年 10 月至 2018 年 1 月，在中国重庆陆军军医大学第二附属医院，对 342 例连续新诊断的稳定型心绞痛门诊患者进行了横断面调查。采用 36 项简明健康调查问卷评估了 8 个 HRQL 维度，包括身体机能、因身体问题导致的角色受限、身体疼痛、一般健康、活力、社会功能、因情绪问题导致的角色受限和心理健康。计算了身体和心理成分摘要。采用多元逐步回归分析确定与 HRQL 相关的因素。
年龄较大、女性、不运动、教育程度较低、月收入较低、有吸烟/饮酒习惯、患有糖尿病、高血压或高脂血症的患者身体 HRQL 评分较低，而年龄较大、教育程度较低和月收入较低的患者心理 HRQL 评分较低。多元逐步回归分析结果表明，身体和心理 HRQL 与运动和月收入呈正相关，与年龄呈负相关。月收入≥5000 元的患者 HRQL 评分高于月收入<5000 元的患者。睡眠质量和饮酒与身体 HRQL 呈负相关，但与心理 HRQL 无关。
我们的研究结果表明，运动和个人收入水平是可改变的因素，与身体和心理 HRQL 呈正相关。这些发现可能对改善稳定型心绞痛患者 HRQL 的临床建议和策略具有启示意义。
