Ma Xuezheng, Liu Fang, Liu Lijuan, Zhang Liping, Lu Mingzhu, Abudukadeer Abuduzhayier, Wang Lingbing, Tian Feng, Zhen Wei, Yang Pengfei, Hu Kongxin
Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, No. 11 Ronghua South St., Beijing, 100176, China.
Gansu International Travel Healthcare Center, Lanzhou, No.387 Jiayuguan E. Rd, Gansu, 730001, China.
BMC Infect Dis. 2017 Nov 10;17(1):715. doi: 10.1186/s12879-017-2791-0.
There is global health concern that the mass movement of pilgrims to and from Mecca annually could contribute to the international spread of Middle East Respiratory Syndrome Coronavirus (MERS-CoV). In China, about 11,000 Muslim pilgrims participate in the Hajj gathering in Mecca annually. This is the first report of MERS-CoV and respiratory virus molecular screening of returning pilgrims at points of entry in China from 2013 to 2015.
A total of 847 returning Hajj pilgrims participated in this study. The test results indicated that of the travelers, 34 tested positive for influenza A virus, 14 for influenza B virus, 4 for metapneumo virus, 2 for respiratory syncytial virus, and 3 for human coronavirus. There was a significant difference in the rates of positive and negative influenza virus tests between Hajj pilgrims with symptoms and those without. The detection rates of influenza virus were not significantly different among the three years studied, at 5.3, 6.0 and 6.3% for 2013, 2014 and 2015, respectively. DISCUSSION AND CONCLUSION: The MERS-CoV and respiratory viruses detection results at points of entry in China from 2013 to 2015 indicated that there were no MERS-CoV infection but a 5.7% positive influenza viruses in returning Chinese pilgrims.
全球对每年往返麦加的朝圣者大规模流动可能促成中东呼吸综合征冠状病毒（MERS-CoV）的国际传播表示担忧。在中国，每年约有11,000名穆斯林朝圣者参加在麦加举行的朝觐活动。这是2013年至2015年在中国入境点对返回的朝圣者进行MERS-CoV和呼吸道病毒分子筛查的首份报告。
共有847名返回的朝觐朝圣者参与了本研究。检测结果显示，这些旅行者中，34人甲型流感病毒检测呈阳性，14人乙型流感病毒检测呈阳性，4人偏肺病毒检测呈阳性，2人呼吸道合胞病毒检测呈阳性，3人人类冠状病毒检测呈阳性。有症状和无症状的朝觐朝圣者之间流感病毒检测的阳性和阴性率存在显著差异。在所研究的三年中，流感病毒的检出率没有显著差异，2013年、2014年和2015年分别为5.3%、6.0%和6.3%。讨论与结论：2013年至2015年在中国入境点的MERS-CoV和呼吸道病毒检测结果表明，返回的中国朝圣者中没有MERS-CoV感染，但流感病毒阳性率为5.7%。
