Haji Kavi, Haji Darsim, Canty David J, Royse Alistair G, Tharmaraj Dhaksha, Azraee Meor, Hopkins Lynda, Royse Collin F
Intensive Care Unit, Frankston Hospital, Frankston, Victoria, Australia; Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.
Frankston Hospital, Frankston, Victoria, Australia; Ultrasound Simulation, Department of Surgery, University of Melbourne, Melbourne, Australia.
J Cardiothorac Vasc Anesth. 2018 Feb;32(1):354-360. doi: 10.1053/j.jvca.2017.08.026. Epub 2017 Aug 18.
Limited transthoracic echocardiography (TTE) and lung ultrasound increasingly is performed in the intensive care unit (ICU), though used in a goal-directed rather than routine manner.
Prospective observational study.
Tertiary ICU.
Ninety-three critically ill participants within 24 hours of admission to ICU.
A treating intensivist documented a clinical diagnosis and management plan before and after combined limited TTE and lung ultrasound. Ultrasound was performed by an independent intensivist and checked for accuracy offline by a second reviewer.
Ultrasound images were interpretable in 99%, with good interobserver agreement. The hemodynamic diagnosis was altered in 66% of participants, including new (14%) or altered (25%) abnormal states or exclusion of clinically diagnosed abnormal state (27%). Valve pathology of at least moderate severity was diagnosed for mitral regurgitation (7%), aortic stenosis (1%), aortic stenosis and mitral regurgitation (1%), tricuspid regurgitation (3%), and 1 case of mitral regurgitation was excluded. Lung pathology diagnosis was changed in 58% of participants including consolidation (13%), interstitial syndrome (4%), and pleural effusion (23%), and exclusion of clinically diagnosed consolidation (6%), interstitial syndrome (3%), and pleural effusion (9%). Management changed in 65% of participants including increased (12%) or decreased (23%) fluid therapy, initiation (10%), changing (6%) or cessation (9%) of inotropic, vasoactive or diuretic drugs, non-invasive ventilation (3%), and pleural drainage (2%).
Routine screening of patients with combined limited TTE and lung ultrasound on admission to ICU is feasible and frequently alters diagnosis and management.
在重症监护病房(ICU)中,经胸壁超声心动图(TTE)检查范围受限,肺部超声检查的应用越来越多,不过这些检查是目标导向性的,而非常规检查。
前瞻性观察性研究。
三级ICU。
93名在入住ICU后24小时内的危重症患者。
一名主治重症医学专家记录了联合进行有限TTE检查和肺部超声检查前后的临床诊断及管理计划。超声检查由一名独立的重症医学专家进行,另一名审阅者离线检查其准确性。
99%的超声图像可解读,观察者间一致性良好。66%的参与者血流动力学诊断发生改变,包括新出现(14%)或改变(25%)的异常状态,或排除临床诊断的异常状态(27%)。诊断出至少中度严重程度的瓣膜病变,二尖瓣反流(7%)、主动脉瓣狭窄(1%)、主动脉瓣狭窄合并二尖瓣反流(1%)、三尖瓣反流(3%),排除1例二尖瓣反流。58%的参与者肺部病理诊断发生改变,包括实变(13%)、间质综合征(4%)、胸腔积液(23%),以及排除临床诊断的实变(6%)、间质综合征(3%)和胸腔积液(9%)。65%的参与者管理发生改变,包括增加(12%)或减少(23%)液体治疗、开始(10%)、改变(6%)或停止(9%)使用血管活性药物、血管活性药物或利尿剂,无创通气(3%),以及胸腔引流(2%)。
对入住ICU的患者常规联合进行有限TTE检查和肺部超声检查是可行的,且经常会改变诊断和管理。