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常规联合有限经胸超声心动图和肺部超声对重症监护病房患者诊断和管理的可行性及影响:一项前瞻性观察研究

The Feasibility and Impact of Routine Combined Limited Transthoracic Echocardiography and Lung Ultrasound on Diagnosis and Management of Patients Admitted to ICU: A Prospective Observational Study.

作者信息

Haji Kavi, Haji Darsim, Canty David J, Royse Alistair G, Tharmaraj Dhaksha, Azraee Meor, Hopkins Lynda, Royse Collin F

机构信息

Intensive Care Unit, Frankston Hospital, Frankston, Victoria, Australia; Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.

Frankston Hospital, Frankston, Victoria, Australia; Ultrasound Simulation, Department of Surgery, University of Melbourne, Melbourne, Australia.

出版信息

J Cardiothorac Vasc Anesth. 2018 Feb;32(1):354-360. doi: 10.1053/j.jvca.2017.08.026. Epub 2017 Aug 18.

DOI:10.1053/j.jvca.2017.08.026
PMID:29126689
Abstract

OBJECTIVES

Limited transthoracic echocardiography (TTE) and lung ultrasound increasingly is performed in the intensive care unit (ICU), though used in a goal-directed rather than routine manner.

DESIGN

Prospective observational study.

SETTINGS

Tertiary ICU.

PARTICIPANTS

Ninety-three critically ill participants within 24 hours of admission to ICU.

METHODS

A treating intensivist documented a clinical diagnosis and management plan before and after combined limited TTE and lung ultrasound. Ultrasound was performed by an independent intensivist and checked for accuracy offline by a second reviewer.

RESULTS

Ultrasound images were interpretable in 99%, with good interobserver agreement. The hemodynamic diagnosis was altered in 66% of participants, including new (14%) or altered (25%) abnormal states or exclusion of clinically diagnosed abnormal state (27%). Valve pathology of at least moderate severity was diagnosed for mitral regurgitation (7%), aortic stenosis (1%), aortic stenosis and mitral regurgitation (1%), tricuspid regurgitation (3%), and 1 case of mitral regurgitation was excluded. Lung pathology diagnosis was changed in 58% of participants including consolidation (13%), interstitial syndrome (4%), and pleural effusion (23%), and exclusion of clinically diagnosed consolidation (6%), interstitial syndrome (3%), and pleural effusion (9%). Management changed in 65% of participants including increased (12%) or decreased (23%) fluid therapy, initiation (10%), changing (6%) or cessation (9%) of inotropic, vasoactive or diuretic drugs, non-invasive ventilation (3%), and pleural drainage (2%).

CONCLUSION

Routine screening of patients with combined limited TTE and lung ultrasound on admission to ICU is feasible and frequently alters diagnosis and management.

摘要

目的

在重症监护病房(ICU)中,经胸壁超声心动图(TTE)检查范围受限,肺部超声检查的应用越来越多,不过这些检查是目标导向性的,而非常规检查。

设计

前瞻性观察性研究。

地点

三级ICU。

参与者

93名在入住ICU后24小时内的危重症患者。

方法

一名主治重症医学专家记录了联合进行有限TTE检查和肺部超声检查前后的临床诊断及管理计划。超声检查由一名独立的重症医学专家进行,另一名审阅者离线检查其准确性。

结果

99%的超声图像可解读,观察者间一致性良好。66%的参与者血流动力学诊断发生改变,包括新出现(14%)或改变(25%)的异常状态,或排除临床诊断的异常状态(27%)。诊断出至少中度严重程度的瓣膜病变,二尖瓣反流(7%)、主动脉瓣狭窄(1%)、主动脉瓣狭窄合并二尖瓣反流(1%)、三尖瓣反流(3%),排除1例二尖瓣反流。58%的参与者肺部病理诊断发生改变,包括实变(13%)、间质综合征(4%)、胸腔积液(23%),以及排除临床诊断的实变(6%)、间质综合征(3%)和胸腔积液(9%)。65%的参与者管理发生改变,包括增加(12%)或减少(23%)液体治疗、开始(10%)、改变(6%)或停止(9%)使用血管活性药物、血管活性药物或利尿剂,无创通气(3%),以及胸腔引流(2%)。

结论

对入住ICU的患者常规联合进行有限TTE检查和肺部超声检查是可行的,且经常会改变诊断和管理。

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